Organic Acids Test (OAT) - Nutritional and Metabolic Profile
UrinePerformed by: Mosaic Diagnostics
Organic acids are chemical compounds excreted in the urine of mammals that are products of metabolism. Metabolism is the sum of chemical reactions in living beings by which the body builds new molecules and breaks down molecules to eliminate waste products and produce energy. Organic acids are organic compounds that are acidic. Organic acids are substances in which carbon and hydrogen are always present but may also contain the elements of oxygen, nitrogen, sulfur, and phosphorus.
The Organic Acids Test offers a comprehensive metabolic snapshot of a patient’s overall health with 75 markers. It provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue, and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, and genetic factors.
Why Run an Organic Acids Test (OAT)?
The Organic Acids Test (OAT) is a simple and efficient way to assess a number of metabolic pathways providing insight into imbalances and nutrient needs. The OAT can provide insight into a wide range of conditions, making it valuable for individuals who are experiencing complex chronic conditions.
The OAT test report is organized into clinically useful categories including:
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Intestinal Microbial Overgrowth markers evaluate for candida activity, clostridia bacteria toxins, potential mold exposure, and imbalance in the gut microflora.
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Oxalate Metabolites provide insight into oxalate levels being generated by organisms within the system or via dietary contributions.
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Glycolytic Cycle Metabolites and Mitochondrial Markers (Krebs Cycle and Amino Acid Metabolites) evaluate for metabolic efficiency (e.g., use of glucose and amino acids for energy generation) and mitochondrial dysfunction.
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Neurotransmitter Metabolites evaluate for phenylalanine, tyrosine and tryptophan metabolism which are linked to neurotransmitter status and quinolinic acid production.
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Pyrimidine Metabolites & Ketone and Fatty Acid Oxidation markers give insight into folate status and cellular turnover, as well as mitochondrial utilization of fatty acids for energy production.
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Nutritional Markers provide insight into the sufficiency of essential vitamins, antioxidants, and metabolic pathway co-factors.
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Indicators of Detoxification assess for the presence of oxidative stress via markers of glutathione sufficiency and methylation versus transsulfuration function.
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Amino Acid Metabolites may suggest functional nutrient need or be reflective of genetic metabolic dysfunction if a consistently, persistently elevated level of a particular analyte is noted.
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The Mineral Metabolism marker provides insight into dietary intake of phosphate and can give insights into Vitamin D levels.
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Biomarkers included in this panel:
What is 2-Hydroxybutyric acid? 2-Hydroxybutyric acid (aka α-Hydroxybutyrate) is a by-product of glutathione production. Levels of 2-Hydroxybutyric acid in the urine may reflect levels of glutathione production. What is Glutathione? Glu
Learn moreWhat is 2-Hydroxybutyric acid? 2-Hydroxybutyric acid (aka α-Hydroxybutyrate) is a by-product of glutathione production. Levels of 2-Hydroxybutyric acid in the urine may reflect levels of glutathione production. What is Glutathione? Glu
Learn moreWhat is 2-Hydroxybutyric acid? 2-Hydroxybutyric acid (aka α-Hydroxybutyrate) is a by-product of glutathione production. Levels of 2-Hydroxybutyric acid in the urine may reflect levels of glutathione production. What is Glutathione? Glu
Learn more2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.
Learn more2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.
Learn more2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.
Learn more2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.
Learn more2-Hydroxyisocaproic acid (aka Leucic acid / α-hydroxyisocaproic acid / HICA) is a metabolite of the branched-chain amino acid leucine.
Learn more2-Hydroxyisocaproic acid (aka Leucic acid / α-hydroxyisocaproic acid / HICA) is a metabolite of the branched-chain amino acid leucine.
Learn more2-Hydroxyisovaleric acid (aka 2-Hydroxy-3-methylbutyric acid) is a branched-chain amino acid metabolite.
Learn more2-Hydroxyisovaleric acid (aka 2-Hydroxy-3-methylbutyric acid) is a branched-chain amino acid metabolite.
Learn more2-Hydroxyisovaleric acid (aka 2-Hydroxy-3-methylbutyric acid) is a branched-chain amino acid metabolite.
Learn moreThe metabolite of phenylalanine via phenyl pyruvate.
Learn moreThe metabolite of phenylalanine via phenyl pyruvate.
Learn moreThe metabolite of phenylalanine via phenyl pyruvate.
Learn more2-Oxo-4-methylthiobutanoic acid, also known as 4-(methylsulfanyl)-2-oxobutanoate or 2-keto-4-methylthiobutyrate, belongs to the class of organic compounds known as thia fatty acids. Thia substituted fatty acids are saturated
Learn more2-Oxo-4-methylthiobutanoic acid, also known as 4-(methylsulfanyl)-2-oxobutanoate or 2-keto-4-methylthiobutyrate, belongs to the class of organic compounds known as thia fatty acids. Thia substituted fatty acids are saturated
Learn more2-Oxoglutaric acid is an organic acid that is important for the proper metabolism of all essential amino acids. It is formed in the Krebs cycle, the energy-producing process that occurs in most body cells.
Learn more2-Oxoglutaric acid is an organic acid that is important for the proper metabolism of all essential amino acids. It is formed in the Krebs cycle, the energy-producing process that occurs in most body cells.
Learn more2-Oxoisocaproic acid (also known as Ketoleucine) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 2-Oxoisocaproic acid is both a neurotoxin and a metabotoxin.
Learn more2-Oxoisocaproic acid (also known as Ketoleucine) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 2-Oxoisocaproic acid is both a neurotoxin and a metabotoxin.
Learn more2-Oxoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids (=BCAA). 2-Oxoisovaleric acid is a neurotoxin, an acidogen, and a metabotoxin.
Learn more2-Oxoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids (=BCAA). 2-Oxoisovaleric acid is a neurotoxin, an acidogen, and a metabotoxin.
Learn more- A precursor in the production of cholesterol in both humans and yeast. - Elevated levels may also indicate decreased CoQ10 synthesis. - Moderate increases are probably due to yeast overgrowth of the GI tract and might also implicate yeast ove
Learn more- A precursor in the production of cholesterol in both humans and yeast. - Elevated levels may also indicate decreased CoQ10 synthesis. - Moderate increases are probably due to yeast overgrowth of the GI tract and might also implicate yeast ove
Learn more3-Hydroxybutyric acid is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis. This acid is metabolized by 3-hydroxybutyrate dehydrogenase. The enzyme f
Learn more3-Hydroxybutyric acid is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis. This acid is metabolized by 3-hydroxybutyrate dehydrogenase. The enzyme f
Learn more3-Hydroxybutyric acid is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis. This acid is metabolized by 3-hydroxybutyrate dehydrogenase. The enzyme f
Learn more3-Hydroxyglutaric is a marker for glutaryl CoA dehydrogenase deficiency.
Learn more3-Hydroxyglutaric is a marker for glutaryl CoA dehydrogenase deficiency.
Learn more3-Indoleacetic is a Tryptophan byproduct of Clostria: C. stricklandii, C. litusburense, C. subterminale, and C. putrefaciens.
Learn more3-Indoleacetic is a Tryptophan byproduct of Clostria: C. stricklandii, C. litusburense, C. subterminale, and C. putrefaciens.
Learn more3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. Moderate increase may result from lactic acidosis, episodic ketosis, or thiamine/lipoic acid deficiency. Significan
Learn more3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. Moderate increase may result from lactic acidosis, episodic ketosis, or thiamine/lipoic acid deficiency. Significan
Learn more3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. Moderate increase may result from lactic acidosis, episodic ketosis, or thiamine/lipoic acid deficiency. Significan
Learn moreThe marker, 3-methylglutaconic acid in high values indicates a reduced ability to metabolize the amino acid, leucine. This abnormality is found in the genetic disease, methylglutaconic aciduria and in mitochondrial disorders.
Learn moreThe marker, 3-methylglutaconic acid in high values indicates a reduced ability to metabolize the amino acid, leucine. This abnormality is found in the genetic disease, methylglutaconic aciduria and in mitochondrial disorders.
Learn more3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.
Learn more3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.
Learn more3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.
Learn more3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.
Learn more3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract.
Learn more3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract.
Learn more3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract.
Learn more4-Cresol has been used as a specific marker for Clostridium difficile.
Learn more4-Cresol has been used as a specific marker for Clostridium difficile.
Learn more4-Hydroxybenzoic Acid is a marker for intestinal dysbiosis.
Learn more4-Hydroxybenzoic Acid is a marker for intestinal dysbiosis.
Learn more4-Hydroxybenzoic Acid is a marker for intestinal dysbiosis.
Learn moreA moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria
Learn moreA moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria
Learn moreA moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria
Learn moreA moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria
Learn more4-Hydroxyhippuric is a glycine conjugate of 4-hydroxybenzoic acid, the paraben metabolite.
Learn more4-Hydroxyhippuric is a glycine conjugate of 4-hydroxybenzoic acid, the paraben metabolite.
Learn more4-Hydroxyhippuric is a glycine conjugate of 4-hydroxybenzoic acid, the paraben metabolite.
Learn moreA tyrosine metabolic product of GI bacteria.
Learn moreA tyrosine metabolic product of GI bacteria.
Learn moreA tyrosine metabolic product of GI bacteria.
Learn moreA tyrosine metabolic product of GI bacteria.
Learn more4-hydroxyphenyllactate is present in relatively higher concentrations in the cerebrospinal fluid and urine of patients with phenylketonuria (PKU) and tyrosinemia.
Learn more4-hydroxyphenyllactate is present in relatively higher concentrations in the cerebrospinal fluid and urine of patients with phenylketonuria (PKU) and tyrosinemia.
Learn more5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin is a hormone found at high levels in many body tissues. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels
Learn more5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin is a hormone found at high levels in many body tissues. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels
Learn moreA metabolite produced by Aspergillus and possibly other fungal species in the GI tract.
Learn moreA metabolite produced by Aspergillus and possibly other fungal species in the GI tract.
Learn moreA metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth levels.
Learn moreAcetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Learn moreAcetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Learn moreAcetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Learn moreElevated in mitochrondrial disorders. Aconitase metabolizes citric and aconitic acids, and is dependent on glutathione.
Learn moreElevated in mitochrondrial disorders. Aconitase metabolizes citric and aconitic acids, and is dependent on glutathione.
Learn moreElevated in mitochrondrial disorders. Aconitase metabolizes citric and aconitic acids, and is dependent on glutathione.
Learn moreAdipic Acid, together with Suberate and Ethylmalonate are all functional markers for deficiency of carnitine.
Learn moreAdipic Acid, together with Suberate and Ethylmalonate are all functional markers for deficiency of carnitine.
Learn moreAdipic Acid, together with Suberate and Ethylmalonate are all functional markers for deficiency of carnitine.
Learn moreBreakdown product of hyaluronic acid; also found in certain foods.
Learn moreProduced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation of the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose. Antifungal treatment and high-potency, multi-s
Learn moreBreakdown product of hyaluronic acid; also found in certain foods.
Learn moreProduced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation of the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose. Antifungal treatment and high-potency, multi-s
Learn moreAscorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibro
Learn moreAscorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibro
Learn moreAscorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibro
Learn moreCarboxycitric is a metabolite of yeast/fungi and general indicator of gastrointestinal dysbiosis. Elevated yeast/fungal metabolites indicate overgrowth in the GI tract.
Learn moreCarboxycitric is a metabolite of yeast/fungi and general indicator of gastrointestinal dysbiosis. Elevated yeast/fungal metabolites indicate overgrowth in the GI tract.
Learn moreMetabolite of yeast or anaerobic bacteria, including Clostridia.
Learn moreMetabolite of yeast or anaerobic bacteria, including Clostridia.
Learn moreCitric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells.
Learn moreCitric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells.
Learn moreCitric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells.
Learn moreProduced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.
Learn moreProduced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.
Learn moreProduced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.
Learn moreHVA and DOPAC are the major metabolites of dopamine.
Learn moreHVA and DOPAC are the major metabolites of dopamine.
Learn moreHVA and DOPAC are the major metabolites of dopamine.
Learn moreHVA and DOPAC are the major metabolites of dopamine.
Learn moreEthylmalonate, together with Adipate and Suberate, gives information about your ability to process fatty acids.
Learn moreFumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.
Learn moreFumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.
Learn moreFumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.
Learn moreFuran 2,5-dicarboxylic is a byproduct of Aspergillus and other fungal species.
Learn moreFuran 2,5-dicarboxylic is a byproduct of Aspergillus and other fungal species.
Learn moreFurancarbonylglycine is a metabolite produced by Aspergillus and possibly other fungal species in the GI tract.
Learn moreA metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.
Learn moreFurancarbonylglycine is a metabolite produced by Aspergillus and possibly other fungal species in the GI tract.
Learn moreA metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.
Learn moreGlutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.
Learn moreGlutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.
Learn moreGlutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.
Learn moreGlutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.
Learn moreThe organic acids test by Great Plains Laboratory measures a few oxalate metabolites which can determine if someone has high oxalate levels. These include oxalic, glycolic, and glyceric. In humans and in yeast, glyoxalate is the parent compound th
Learn moreNormal values rule out genetic causes of significantly elevated urinary oxalic acid.
Learn moreNormal values rule out genetic causes of significantly elevated urinary oxalic acid.
Learn moreIndicator of genetic disease of oxalate metabolism called Hyperoxaluria type I due to a deficiency in the enzyme activity of alanine glyoxylate amino transferase (AGT).
Learn moreIndicator of genetic disease of oxalate metabolism called Hyperoxaluria type I due to a deficiency in the enzyme activity of alanine glyoxylate amino transferase (AGT).
Learn moreHippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic aci
Learn moreHippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic aci
Learn moreHippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic aci
Learn moreHomogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA). Elevated in the genetic disease homogentisic aciduria (alkaptonuria).
Learn moreHomogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA). Elevated in the genetic disease homogentisic aciduria (alkaptonuria).
Learn moreHomovanillate (aka Homovanillic Acid) is a dopamine metabolite. Homovanillate and Vanilmandelate are breakdown products from neurotransmitters involved in hormone and nerve impulse transmission, called catecholamines.
Learn moreHomovanillate (aka Homovanillic Acid) is a dopamine metabolite. Homovanillate and Vanilmandelate are breakdown products from neurotransmitters involved in hormone and nerve impulse transmission, called catecholamines.
Learn moreHPHPA is a clostridia metabolite and dysbiosis marker and stands for 3-(3-hydroxyphenyl)-3-hydroxypropionic acid.
Learn moreHPHPA is a clostridia metabolite and dysbiosis marker and stands for 3-(3-hydroxyphenyl)-3-hydroxypropionic acid.
Learn moreHPHPA is a clostridia metabolite and dysbiosis marker and stands for 3-(3-hydroxyphenyl)-3-hydroxypropionic acid.
Learn moreThe Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.
Learn moreThe Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.
Learn moreThe Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.
Learn moreHVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.
Learn moreHVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.
Learn moreKynurenic Acid is product of the metabolism of L-Tryptophan and appears in urine in Vitamin B6 deficiencies. Your body needs vitamin B6 (pyridoxine) to utilize amino acids derived from dietary protein.
Learn moreKynurenic Acid is product of the metabolism of L-Tryptophan and appears in urine in Vitamin B6 deficiencies. Your body needs vitamin B6 (pyridoxine) to utilize amino acids derived from dietary protein.
Learn moreFormed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.
Learn moreFormed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.
Learn moreFormed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.
Learn moreMalic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.
Learn moreMalic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.
Learn moreMalic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.
Learn moreMalonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competiti
Learn moreMalonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competiti
Learn moreMandelic acid is the major metabolite of styrene. Styrene (vinylbenzene) is used as an intermediate in plastic synthesis. Values less than 5 mg/L are due to normal metabolism of phenylalanine or tyrosine.
Learn moreMandelic acid is the major metabolite of styrene. Styrene (vinylbenzene) is used as an intermediate in plastic synthesis. Values less than 5 mg/L are due to normal metabolism of phenylalanine or tyrosine.
Learn moreMethylcitric is an organic acids that reflects decreased activity of the biotin-dependent enzyme propionyl-CoA carboxylase.
Learn moreMethylcitric is an organic acids that reflects decreased activity of the biotin-dependent enzyme propionyl-CoA carboxylase.
Learn moreMethylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Learn moreMethylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Learn moreMethylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids.
Learn moreMethylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids.
Learn moreMethylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids.
Learn moreElevated N-acetylaspartic acid is due to the genetic disorder Carnavan’s disease, a potentially fatal disease causing spongy degeneration of the brain. What is Carnavan’s disease? Canavan disease is a rare inherited disorder t
Learn moreElevated N-acetylaspartic acid is due to the genetic disorder Carnavan’s disease, a potentially fatal disease causing spongy degeneration of the brain. What is Carnavan’s disease? Canavan disease is a rare inherited disorder t
Learn moreN-Acetylcysteine (NAC) is a powerful antioxidant that increases the glutathione reserves in the body. Together with glutathione, N-Acetylcysteine (NAC) directly binds to toxic metabolites. Although N-Acetylcysteine (NAC) may be benefici
Learn moreN-Acetylcysteine (NAC) is a powerful antioxidant that increases the glutathione reserves in the body. Together with glutathione, N-Acetylcysteine (NAC) directly binds to toxic metabolites. Although N-Acetylcysteine (NAC) may be benefici
Learn moreOrotic Acid is a sensitive marker of your liver’s capacity to convert toxic ammonia to non-toxic urea that you can excrete. That capacity can be increased by additional arginine. Ammonia toxicity can also be reduced by
Learn moreOrotic Acid is a sensitive marker of your liver’s capacity to convert toxic ammonia to non-toxic urea that you can excrete. That capacity can be increased by additional arginine. Ammonia toxicity can also be reduced by
Learn moreOrotic Acid is a sensitive marker of your liver’s capacity to convert toxic ammonia to non-toxic urea that you can excrete. That capacity can be increased by additional arginine. Ammonia toxicity can also be reduced by
Learn moreOxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin
Learn moreOxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin
Learn moreOxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin
Learn moreOxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin
Learn morePantothenic acid is an essential B vitamin (=Vitamin B5) that is converted to coenzyme A (unrelated to vitamin A). Coenzyme A is needed for the synthesis of fatty acids, cholesterol, and acetyl choline and is also needed for the Krebs cycle and fatty
Learn morePantothenic acid is an essential B vitamin (=Vitamin B5) that is converted to coenzyme A (unrelated to vitamin A). Coenzyme A is needed for the synthesis of fatty acids, cholesterol, and acetyl choline and is also needed for the Krebs cycle and fatty
Learn morePantothenic acid is an essential B vitamin (=Vitamin B5) that is converted to coenzyme A (unrelated to vitamin A). Coenzyme A is needed for the synthesis of fatty acids, cholesterol, and acetyl choline and is also needed for the Krebs cycle and fatty
Learn morePhenyllactic acid is a metabolite of phenylalanine.
Learn morePhenyllactic acid is a metabolite of phenylalanine.
Learn morePhenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor.
Learn morePhenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor.
Learn morePhosphoric acid is a marker of vitamin D and calcium. This marker indicates whether vitamin D receptors are activated. If phosphoric acid is low, then the person is likely vitamin D and/or calcium deficient. Low levels can be due to low phosphat
Learn morePhosphoric acid is a marker of vitamin D and calcium. This marker indicates whether vitamin D receptors are activated. If phosphoric acid is low, then the person is likely vitamin D and/or calcium deficient. Low levels can be due to low phosphat
Learn moreA major metabolite of vitamin B6. High pyridoxic acid indicates high recent intake of vitamin B6. Because some individuals may require very high doses of vitamin B6, high values do not necessarily indicate the need to reduce vitamin B6 intake. Low va
Learn moreThe main urinary metabolite of pyridoxine (Vitamin B6) and is a measure of recent dietary intake. Low values of pyridoxic acid in the urine indicate low recent intake while high values indicate high recent dietary intake.
Learn morePyroglutamate (or Pyroglutamic acid) is an intermediate in the glutathione metabolism and a marker of glutathione deficiency.
Learn morePyroglutamate (or Pyroglutamic acid) is an intermediate in the glutathione metabolism and a marker of glutathione deficiency.
Learn morePyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids.
Learn morePyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids.
Learn morePyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids.
Learn moreQuinolinic acid is a neurotoxic substance produced by our own bodies and a metabolite of tryptophan.
Learn moreQuinolinic acid is a neurotoxic substance produced by our own bodies and a metabolite of tryptophan.
Learn moreA high ratio of quinolinic acid to the tryptophan metabolite, 5-hydroxyindoleacetic acid, indicates excessive inflammation due to recurrent infections, excessive tryptophan intake, immune overstimulation, excessive adrenal production of cortisol, or
Learn moreIncreased urinary products of the omega fatty acid metabolism pathway may be due to carnitine deficiency, fasting, or increased intake of triglycerides from coconut oil, or some infant formulas.
Learn moreIncreased urinary products of the omega fatty acid metabolism pathway may be due to carnitine deficiency, fasting, or increased intake of triglycerides from coconut oil, or some infant formulas.
Learn moreSuberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.
Learn moreSuberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.
Learn moreSuberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.
Learn moreSuccinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.
Learn moreSuccinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.
Learn moreSuccinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.
Learn moreBreakdown product of hyaluronic acid; also found in some foods.
Learn moreBreakdown product of hyaluronic acid; also found in some foods.
Learn moreBreakdown product of hyaluronic acid; also found in some foods.
Learn moreA pyrimidine (DNA building block) that is elevated in the genetic disease dihydropyrimidine dehydrogenase deficiency. In this genetic disease, the pyrimidine uracil is also elevated. - Thymine is one of the five bases used to build nucleic acids.
Learn moreA pyrimidine (DNA building block) that is elevated in the genetic disease dihydropyrimidine dehydrogenase deficiency. In this genetic disease, the pyrimidine uracil is also elevated. - Thymine is one of the five bases used to build nucleic acids.
Learn moreA chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate
Learn moreA chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate
Learn moreA chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate
Learn moreA chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate
Learn moreThe pyrimidine metabolites are markers of folate metabolism. The two markers are uracil and thymine. Folate acts as a methyl donor in converting uracil to thymine. Elevated values of uracil suggest folic acid deficiency. Folate is needed to conver
Learn moreThe pyrimidine metabolites are markers of folate metabolism. The two markers are uracil and thymine. Folate acts as a methyl donor in converting uracil to thymine. Elevated values of uracil suggest folic acid deficiency. Folate is needed to conver
Learn moreThe pyrimidine metabolites are markers of folate metabolism. The two markers are uracil and thymine. Folate acts as a methyl donor in converting uracil to thymine. Elevated values of uracil suggest folic acid deficiency. Folate is needed to conver
Learn moreMetabolite of epinephrine and norepinephrine. Often elevated due to stress induced catecholamine output or lead toxicity.
Learn moreMetabolite of epinephrine and norepinephrine. Often elevated due to stress induced catecholamine output or lead toxicity.
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