Urinary Hormones
Urine
Performed by: Vibrant Wellness
The Vibrant Wellness Urinary Hormones is a test to measure urinary hormones including estrogens, androgens, progesterogens, glucocorticoids and oxidative stress. The panel is designed to give a complete picture of an individual’s levels of hormones and their metabolites in urine. Hormones are essential chemical messengers which regulate routine processes in the body.
Hormones, especially adrenal hormones and sex hormones, are interconnected with neurotransmitters. An imbalance of adrenal and sex hormones could lead to neurotransmitter imbalances which could revert back to cause hormonal imbalances.
Hormone imbalances can affect a wide range of body functions including:
Metabolism and appetite, heart rate, sleep cycles, reproductive cycles and sexual function, general growth and development, mood and stress levels, body temperature.
Conditions or symptoms associated with hormonal imbalances such as:
Hot flashes, night sweats, headaches, hair loss, poor sleep, anxiety, depression, stress, low libido, memory lapse, sugar cravings, weight gain, dry/dull appearance of skin, poor stamina, decreased muscle mass/strength, neck/back pain, decreased urinary flow (men), thinning hair, eyebrows, or eyelashes, erectile dysfunction, apathy/mood changes, poor cognition, brain fog, fatigue, chronic irritability, increased facial hair/acne, irregular menstrual cycles.
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Biomarkers included in this panel:
2-hydroxyestrone and 16-hydroxyestrone are Phase I metabolites of Estrone (E1). Their ratio is of clinical significance in pre and peri-menopausal women. In post-menopausal women it does not have the same clinical significance. It is, however, hypoth
Learn moreThe hydroxylation of estradiol is one of the major routes of metabolism of the estrogen steroid hormone estradiol. It is hydroxylated into the catechol estrogens 2-hydroxyestradiol and 4-hydroxyestradiol and into estriol (16a-hydroxyestradiol). 2-hyd
Learn moreHealthy Phase II metabolism methylates 2-hydroxy (2-OH) estrogens to the more cancer-protective 2-methoxy (2-MeO) forms, and neutralizes the potentially carcinogenic 4-OH estrogens to their 4-MeO forms.
Learn moreThe hydroxylation of estradiol is one of the major routes of metabolism of the estrogen steroid hormone estradiol. It is hydroxylated into the catechol estrogens 2-hydroxyestradiol and 4-hydroxyestradiol and into estriol (16α-hydroxyestradiol).
Learn more8-hydroxy-2’-deoxyguanosine (8-OHdG, or 8-oxodG) is a marker of oxidative stress. Urinary 8-OHdG, in particular, has been measured most frequently to indicate the extent of oxidative damage. guanine is most prone to oxidation. Guanine molecule,
Learn moreThis is one of the three cortisol metabolites. The total some of the three cortisol metabolites gives us a good indication of the overall cortisol production in your body. Two of the 3 metabolites are the active form of cortisol (THF). The o
Learn moreb-Pregnanediol is a metabolite of the molecule of progesterone, which is important for fertility and for menstruation. Pregnanediol levels increase after ovulation and when the placenta releases the hormone. Low progesterone symptoms include hot flas
Learn moreThis ratio is helpful when both E2 and Pg are within range, yet the patient continues to have symptoms. It is not expected to be normal or used clinically when either E2 and/or Pg are outside of their expected ranges or if the patient does not have c
Learn moreb-Tetrahydrocortisone (b-THE) is an adrenal steroid and a cortisol metabolite. Tetrahydrocortison (THE) is a down-stream metabolite of cortisol and cortisone. Cortisone is a pregnane steroid hormone closely related to cortisol. It is one of the ma
Learn moreBisphenol A
Bisphenol A (BPA) is a xenoestrogen, exhibiting estrogen-mimicking, hormone-like properties that raise concern about its suitability in some consumer products and food containers. Bisphenol A (BPA) is an organic synthetic compound and it is a startin
Learn moreCorticosterone, also known as 17-deoxycortisol, is a steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. Corticosterone has multiple effects on memory. The main effects are seen through the impact of stress on emo
Learn moreMetabolized cortisol reflects the total cortisol produced and clearing through the liver, while free-cortisol results tell us how much cortisol is free to bind to receptors and allows for assessment of the circadian rhythm. Cortisol is a steroid h
Learn moreTotal Estrogen
Estrogen is the primary female sex hormone. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens in females that have estrogenic hormonal
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