Complete Hormones FMV - Menopause Female

Urine

Performed by: Genova Diagnostics

Biomarkers included in this panel:

11-Hydroxy-androsterone (FMV urine, menopause)

11-Hydroxy-androsterone is a 5β-reduced compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the

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11-Hydroxy-etiocholanolone (FMV urine, menopause)

11-Hydroxy-etiocholanolone is a compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health

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11-Keto-androsterone (FMV urine, menopause)

11-Keto-androsterone is a that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health of both men and

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11-Keto-etiocholanolone (FMV urine, menopause)

11-Keto-etiocholanolone is a 5β-reduced compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the

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16a-Hydroxyestrone (16a-OH E1) / Menopause

16α-Hydroxyestrone (16α-OH-E1), or hydroxyestrone, also known as estra-1,3,5(10)-trien-3,16α-diol-17-one, is an endogenous steroidal estrogen and a major metabolite of estrone, as well as an intermediate in the biosynthesis of estri

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17 - Hydroxysteroids Total (FMV urine, menopause)

An elevated 17-hydroxysteroids total and/or cortisol total may be caused by stress, strenuous exercise, inflammation, hypoglycemia, insulin resistance, hypothyroidism, or licorice ingestion.

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17 - Ketosteroids Total (FMV urine, menopause)

ANDROGENS such as DHEA, testosterone, and androstenedione tend to be extensively metabolized into downstream androgen compounds. As a result, the levels of testosterone along with “Total 17-ketosteroids” (DHEA plus metabolites) should be

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17-Hydroxysteroids, Total (menopause)

An elevated 17-hydroxysteroids total and/or cortisol total may be caused by stress, strenuous exercise, inflammation, hypoglycemia, insulin resistance, hypothyroidism, or licorice ingestion.

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17-Ketosteroids, Total (FMV urine, menopause)

Testosterone and DHEA are metabolized into what are collectively known as the 17-ketosteroids.

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2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH(E1+E2)] / Menopause

2-Methoxyestrone+2-Methoxyestradiol [2MeO(E1+E2)] / Menopause

2-OH(E1+E2) / 16a-OHE1 (Menopause)

2-OH(E1+E2) / 2-MeO(E1+E2) / Menopause

There is evidence that methoxylated estrogens, especially the 2-pathway methoxylated estrogens (E1 and E2), are associated with decreased breast cancer risk; 2-MeOE2, produced from 2-OHE2, has been described to have anti-proliferative, antingiogenic,

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4-Hydroxyestrone+4-Hydroxyestradiol [4-OH(E1+E2)] / Menopause

Research focus is shifting toward 4-hydroxyesterone which is thought to have greater estrogenic and genotoxic potential than either 2-hydroxyestrone or 16a-hydroxyestrone.

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4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)] / Menopause

Most recent studies find an increased breast cancer risk associated with the ratio of 4-pathway cetechols to 4-pathway methylated catechols.

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allo-Tetrahydrocortisol, a-THF (FMV urine, menopause)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Anabolic/Catabolic Balance (FMV)

Anabolic/Catabolic Balance (FMV, menopause)

The Anabolic/Catabolic Balance refers to the balance between "growth and healing" (anabolic) and "wear and tear" (catabolic) activity in the body. Both anabolic and catabolic metabolism are essential to health.

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Androstanediol (FMV urine, menopause)

The measurement of androstanediol, in addition to testosterone, is of interest for the evaluation of androgenic activity.

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Androsterone (FMV urine, menopause)

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways.

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DHEA (FMV urine, menopause)

DHEA is a hormone produced by both the adrenal gland and the brain. DHEA leads to the production of androgens and estrogens. DHEA levels in the body begin to decrease after age 30. Levels decrease more quickly in women.

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E/A: 5b/5a Ratio (FMV urine, menopause)

The Etiocholanolone/Androsterone (E/A) Ratio assesses androgen metabolism by comparing the enzymatic activity of 5β-reductase/5α-reductase.

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Estradiol (FMV urine, menopause)

The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving abs

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Estriol (FMV urine, menopause)

Has weak estrogen activity. Considered to be a protective estrogen. Most prevalent estrogen in pregnancy.

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Estrone (FMV urine, menopause)

Produced by the ovaries, the estrone hormone is one of three types of estrogen, and it is one of the major hormones found in the bodies of postmenopausal women. While research into estrone function is still ongoing, since it is the least powerful of

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Etiocholanolone (FMV urine, menopause)

Etiocholanolone is an androstenedione and testosterone metabolite that is excreted in the urine. It is produced from androstenedione and the 5-alpha and 5-beta-reductase metabolic pathways. It is helpful in evaluating adrenal and androgen function.

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Pregnanediol (FMV urine, menopause)

Progesterone rapidly metabolizes by the time it reaches the urine, and its direct metabolite, pregnanediol, is a reflection of circulating progesterone concentrations.

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Pregnanetriol (FMV urine, menopause)

Progesterone is metabolized into numerous downstream compounds, but most immediately into pregnanediol and pregnanetriol. Urine levels of these metabolites tend to correlate with levels of serum progesterone, thus may be used to assess status of the

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Testosterone (FMV urine, menopause)

Testosterone is the major androgen in the body. It is converted to dihydrotestosterone by 5-alphareductase, and to estradiol by aromatase.

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Tetrahydrocortisol, THF (FMV urine, menopause)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrocortisone, THE (FMV urine, menopause)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrodeoxycortisol (FMV urine, menopause)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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