The measurement of androstanediol, in addition to testosterone, is of interest for the evaluation of androgenic activity.
Measurement of urinary androstanediol, often in association with testosterone and/or androstenedione, is commonly used to study women with hyperandrogenic syndromes. In particular, high levels of urinary androstanediols have been found in women with idiopathic hirsutism, an endocrine abnormality related to increased activity of two androgen-dependent
structures of the human skin: the hair follicle and the sebaceous gland.
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