Most recent studies find an increased breast cancer risk associated with the ratio of 4-pathway cetechols to 4-pathway methylated catechols. This increased risk has been seen in cases with less extensive methylation of potentially genotoxic 4-hydroxylation pathway catechols; thus, increased relative levels of 4-methoxyestrogens would be considered favorable.
4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)] / Menopause
4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)] / Menopause
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