Array 22 - Irritable Bowel/SIBO Screen

Serum

Performed by: Cyrex Laboratories

-- Identify the overgrowth of large intestinal bacteria in the small intestine and the release of bacterial cytotoxins

-- Evaluate a breach of intestinal barrier by bacterial cytotoxins and their entry into circulation

-- Assist in setting guidelines for treatment of irritable bowels/SIBO and reduce risk of igniting the autoimmune process

Recommended for Patients Who:

-- Have irritable bowels

-- Exhibit symptoms of malabsorption, including weight loss, anemia or fatty stools

-- Have associated conditions such as fatigue, reflux, skin disorders, obesity or food intolerances

Biomarkers included in this panel:

Bacterial Cytotoxins IgM

Bacterial Cytotoxins refer to the cytolethal distending toxin, subunit B (CdtB) that is released by Escherichia coli, Salmonella, Shigella and Campylobacter jejuni. Utilizing subunits A and C, gram-negative bacteria can bind to human cells, allowing

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Cytoskeletal Proteins IgM

Cytoskeletal Proteins is the collective name given to intercellular adherent junctions that are involved in the integrity and functionality of the epithelial barrier. The major cytoskeletal proteins assessed in Array 22 are a-actinin, talin and vincu

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