Genova Diagnostics (various)

Performed by: Genova Diagnostics

Biomarkers included in this panel:

11-Eicosenoic

Eicosenoic acid has recently been reported as one of the five biomarkers for diagnosis of schizophrenia.

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25-Hydroxyvitamin D

Vitamin D is well known for the role it plays in regulating calcium and phosphorus to maintain bone health. Vitamin D insufficiency has been linked to depression and Seasonal Affective Disorder, neurological autoimmune processes, and in preventing on

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a-Hydroxybutyric Acid

a-hydroxybutyric acid (2-hydroxybuturic acid [2-HB]) is a marker that relates to oxidative stress. a-hydroxybutyric acid is an organic acid produced from a-ketobutyrate via the enzymes lactate dehydrogenase (LDH) or a-hydroxybutyrate dehydrogenase

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AA/EPA

This test measures the ratio of arachidonic acid (AA) to eicosapentaenoic acid (EPA) in plasma. This ratio of the principle omega-3 and omega-6 fatty acids is a measure of the body’s eicosanoid balance. Balancing these eicosanoids in the body i

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Alpha Linolenic

Alpha-linolenic acid (ALA) is plant-based essential omega-3 polyunsaturated fatty acids that must be obtained through the diet.

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alpha-Tocopherol

Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) that have varying levels of biological activity. Alpha- (or α-) tocopherol&

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Aluminum

The major tissue sites of aluminum toxicity are the nervous system, immune system, bone, liver, and red blood cells. Aluminum may also interfere with heme (porphyrin) synthesis.

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Arachidic

Arachidic acid (also called eicosanoic acid) is a long-chain saturated fatty acid. It is the elongation product of stearic acid and can be utilized as an energy source to build membranes.

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Arachidonic

Arachidonic acid is an inflammatory omega-6 fatty acid. Our bodies produce this nutrient, and its excess may lead to inflammatory diseases and mood disorders.

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Arsenic

Arsenic is a natural component of the earth’s crust and is widely distributed throughout the environment in the air, water and land. It is highly toxic in its inorganic form and considered a carcinogenic heavy

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Behenic

Behenic acid is a saturated fatty acids, in particular it is part of the group of very long chain fatty acids (VLCFAs).

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Beta-Carotene

Beta-Carotene is an oxidative stress marker. – Beta-Carotene is involved in antioxidant protection. – Beta-carotene is converted into vitamin A in the liver. – Beta-carotene & other carotenoids are converted to vitamin

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Cadmium

The principal organs most vulnerable to cadmium toxicity are your kidney and lung. Environmental cadmium exposure is associated with renal tubular damage and high blood pressure. Cadmium toxicity impacts the kidney, where dam

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Calcium

Calcium is essential for bones and teeth, heart, nerves, muscles, and blood clotting. Calcium is the most abundant mineral element in your body, because it is the major element in bones. Serum and red blood

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Capric

Capric acid (also known as Decanoic acid) is a medium-chain fatty acid (=MCFA) abundant in tropical oils such as coconut oil, whereas small amounts are present in milk of goat, cow, and human. The MCFAs are virtuall

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Coenzyme Q10 (Genova)

CoEnzyme Q10 is an essential component of the mitochondria of the energy producing unit of the cell.

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Copper

Copper is part of enzymes, which are proteins that help biochemical reactions occur in every cell. Copper is involved in the absorption, storage and metabolism of iron.

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Creatinine

Dihomogamma Linolenic (Genova)

Dihomogamma Linolenic Acid (DGLA) is the elongation product of Gamma-linolenic acid (GLA). Dihomo-gamma-linolenic acid (DGLA) is a fatty acid and part of the Omega-6 fatty acids family. Those fatty acids can predominatentely be found in vegetable

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Docosadienoic (Genova)

Docosadienoic acid is an omega-6 fatty acid. Omega-6 fatty acids are a type of polyunsaturated fat found in vegetable oils, nuts and seeds.

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Docosahexaenoic (Genova)

Docosahexaenoic acid (DHA) is one of the omega-3 fatty acids.

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Docosapentaenoic (Genova)

Docosapentaenoic acid, or DPA, is a lesser known member of the omega-3 family.

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Docosatetraenoic (Genova)

Docosatetraenoic acid is also known as Adrenic acid / Adrenate. Docosatetraenoic acid is a member of the class of compounds known as very long-chain fatty acids. Fatty acids belong to one of three types or families: saturated, mo

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Eicosadienoic (Genova)

Eicosadienoic acid is the elongation product of Gamma linolenic acid (GLA) and the direct precursor of Dihomogamma Linolenic (DGLA).

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Eicosapentaenoic (Genova)

Eicosapentaenoic Acid (EPA) is a Polyunsaturated Omega-3 Fatty Acid and is involved in the regulation of inflammatory processes and prevention of blood clots.

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EPA/DGLA (Genova)

The fatty acid profile shows the balance of fats and their metabolites in plasma. Your overall balance of omega-3 and omega-6 fats is represented by the ratios of AA/EPA(arachidonic acid/eicosapentaenoic acid) and EPA/DGLA.

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Gamma Linolenic (Genova)

Gamma-linolenic acid (GLA) is an omega-6 fatty acid. The body converts linoleic acid to gamma-linolenic acid and then to arachidonic acid (AA).  You can get gamma-linolenic acid from several plant-based oils, including evening primrose o

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gamma-Tocopherol (Genova)

Gamma-tocopherol is part of the Vitamin E classification group. The term vitamin E refers to a group of eight naturally occurring compounds, all with different potencies: – alpha-, beta-, gamma- and delta-tocopherol an

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Glyceric Acid

Glyceric acid is an organic acid that stems from the catabolism of the amino acid serine. Severe elevations in glyceric acid are an indication of a rare inborn error of metabolism known as glyceric aciduria. One form of glyceric aciduria is the resul

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Glycolic

Glycolic acid is another byproduct of the oxalate pathway and comes from the conversion of glyoxylic acid. Urinary levels of glycolic acid have most commonly been studied in the rare inborn error of metabolism primary hyperoxaluria type 1 (PH1). PH1

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Heneicosanoic (Genova)

Heneicosanoic acid is an odd-numbered saturated fatty acid. Fatty acids with odd numbers of carbon atoms are produced primarily by initiating the synthetic series with the three carbon compound, propionic acid. Vitamin B12 is required for the

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Heptadecanoic (Genova)

Heptadecanoic Acid is an odd chain fatty acid. Fatty acids with odd numbers of carbon atoms are produced primarily by initiating the synthetic series with the three carbon compound, propionic acid.

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Hexacosanoic (Genova)

Hexacosanoic acid is a saturated fatty acid. It is a very long-chain fatty acid. Accumulation of certain very long chain fatty acids (VLCFAs) is associated with degenerative diseases of the central nervous system.

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LA/DGLA

LA/DGLA is a fatty acid ratio. LA/DGLA stands for linolenic acid (=LA) and dihomogammalinolenic acid (=DGLA). The LA/DGLA ratio is a biomarker that can indicate functional zinc deficiency.

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Lauric (Genova)

Lauric acid is a saturated fat and one of the medium chain fatty acids (MCFAs) together myristic and capric acid.

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Lead (Genova)

Lead toxicity causes paralysis and pain in the extremities due to effects on demyelinization, axonal degeneration, and presynaptic block. Lead toxicity commonly affects sensory, visual, auditory, and cerebellar (coordination) functions, reflecting

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Lignoceric (Genova)

Lignoceric Acid is a saturated fatty acids, in particular it is part of the group of very long chain fatty acids (VLCFAs).

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Linoleic (Genova)

Linoleic acid is by far the most abundant polyunsaturated fatty acid in most human tissues. Linoleic acid is an essential fatty acid, and low levels indicate dietary insufficiency.

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Lipid Peroxides (Genova)

Lipid peroxides are oxidative degradation products of lipids, generated by a free radical chain reaction. Because of their abundance of reactive hydrogens, polyunsaturated fatty acids are highly susceptible to lipid peroxidation, which compromises th

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Magnesium (Genova)

Measuring mineral concentrations inside your erythrocytes (red blood cells) is one of the best ways to determine their adequacy. Minerals are important catalysts that spark many of the chemical reactions in your body. The most extensively required mi

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Mead (Genova)

Mead Acid (plasma) is a marker for overall, essential fatty acid status. 

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Mercury (Genova)

Mercury is an element that is found all over the earth, in soil, rocks, and water. The issue with mercury is that if humans are exposed to it, depending on the amount, route, and duration of exposure, mercury can be toxic to humans.

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Myristic (Genova)

Myristic acid is a medium chain fatty acid (=MCFA). It is present in palm kernel oil, coconut oil, butterfat, milk and to some extent in animal fats.

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Myristoleic (Genova)

Myristoleic acid is one of the monounsaturated fatty acids.

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Nervonic (Genova)

Nervonic acid is a monounsaturated fatty acid. Nervonic acid has the longest carbon chain of all monounsaturated fatty acids. It is found in highest concentrations in nerve membranes, particularly in myelin sheaths, which are sleeves of fat

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Nonadecanoic (Genova)

Nonadecanoic Acid is an odd chain fatty acid. Fatty acids with odd numbers of carbon atoms are produced primarily by initiating the synthetic series with the three carbon compound, propionic acid.

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Oleic (Genova)

Oleic acid is the most common monounsaturated fatty acid in human cells.

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Oxalic Acid

Oxalic acid is the metabolic end-product of the glyoxylase pathway and is derived from the oxidation of glyoxylate. In the cell, the majority of glyoxylate is converted into glycine or glycolic acid. However, in some instances there may be greater ox

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Palmitelaidic

Palmitelaidic acid is a trans fat. Trans fatty acids are prevalent in most diets because of the widespread use of hydrogenated oils used by manufacturers of margarines, bakery products, and peanut butters.

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Palmitic (Genova)

Palmitic acid is a saturated fatty acid. Palmitic and stearic acids are significant markers for high consumption of saturated fats.

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Palmitoleic (Genova)

Palmitoleic acid is a monounsaturated fatty acid. Palmitoleic acid is the desaturation product of palmitic acid. Since palmitic acid is predominant in human tissues where desaturase enzyme activity is present, one might expect relatively high le

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Pentadecanoic (Genova)

Pentadecanoic acid is an odd numbered fatty acid with a 15-carbon backbone (15:0) and widely considered as one biomarker to assess dairy consumption/intake. It is not normally synthesized by humans, but is found in trace amounts in dairy product

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Potassium (Genova)

Erythrocyte potassium levels uniquely reveal your total body potassium status. Potassium is an abundant mineral that helps keep normal water balance between the cells and body fluids. Muscle contractions, nerve impulses and blood pressure rely on ava

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Selenium (Genova)

Selenium is a mineral found in soil, water, and some foods. We need trace amounts for normal health, and selenium is an essential element in several metabolic pathways. It also has antioxidant properties that help prevent cellular damage from free ra

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Stearic (Genova)

Stearic acid is a saturated fatty acid that is two carbon atoms longer than palmitic acid.

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Stearic/Oleic

The stearic acid/oleic acid ratio from red blood cells is a marker for the presence of malignant tissue, particularly with prostate cancer. In tumors, the net result of changes in fatty acid metabolism is low stearic acid and high oleic acid, causing

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Total C:18 Trans

The total C18 trans isomers include elaidic acid, petroselaidic, and transvaccenic acids. The presence of these eighteen-carbon long trans fatty acids in human tissue can disrupt or impair cell membrane function. A person with high levels of total C1

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Tricosanoic (Genova)

Tricosanoic Acid is an odd chain fatty acid. Fatty acids with odd numbers of carbon atoms are produced primarily by initiating the synthetic series with the three carbon compound, propionic acid.

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Triene/Tetraene (Genova)

The Triene/Tetraene (T/T) ratio is another marker for essential fatty acid status. It is calculated as the ratio of Mead acid to arachidonic acid. This ratio, combined with measurements of the essential fatty acids and Mead acid, gives a more complet

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Vaccenic

Vaccenic acid is a naturally occurring trans-fatty acid. Vaccenic acid is called this way as it is found in cow’s milk. The latin word vacca means cow.

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Vitamin A (Retinol) (Genova)

Vitamin A is an antioxidant in the membranes of your cells where it serves a protective function. Every day you lose some vitamin A, because it is used in the replacement of old tissues.

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Zinc (Genova)

Zinc plays a vital role in immunity, protein metabolism, heme synthesis, growth & development, reproduction, digestion and antioxidant function.

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