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Hepatic Detox Profile

Urine

Performed by: Doctor's Data

The body continually attempts to eliminate chemical toxins through enzymatic processes in the liver. Urinary D-glucaric acid, a byproduct of Phase I detoxification, is an indicator of chemical exposure to over 200 chemicals. Urinary mercapturic acids are excreted end products of Phase II detoxification. Together, assessment of these two analytes provides valuable information about exposure to xenobiotics, liver disease and the ability of the liver to eliminate toxins. This non-invasive test requires a single, first morning void (= FMV) urine collection.

Biomarkers included in this panel:

D-Glucaric Acid (Phase I)

The human body attempts to eliminate xenobiotics (foreign organic chemicals) through a concerted effort of enzymatic “functionalization” (phase I) and conjugation (phase II). Functionalization involves chemical modification of the xeno

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Mercapturic Acids (Phase II)

The urinary level of mercapturic acids indicates quantitatively the degree of activity or capability of phase II detoxification. Mercapturic acids are the final excretory products of detoxification and include a variety of functionalized xenobiotics

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