NutrEval Plasma - Urine and Blood
Urine BloodPerformed by: Genova Diagnostics
NutrEval: The Comprehensive Nutritional and Functional Assessment
The NutrEval profile is a leading diagnostic tool for health practitioners seeking to understand the root causes of dysfunction in the body and address clinical imbalances affecting overall health. As one of the most comprehensive nutritional assessments available, NutrEval helps healthcare providers identify nutritional deficiencies and biochemical imbalances, guiding patients toward better health and the prevention of chronic conditions.
What Does the NutrEval Test Assess?
The NutrEval test provides a thorough evaluation of various markers in the body, examining both macronutrients and micronutrients. It also analyzes markers that provide insights into digestion, mitochondrial function, toxic exposure, and oxidative stress. This test includes the measurement of:
- Organic Acids: Indicators of metabolic and digestive function.
- Amino Acids: Assessing protein metabolism and the absorption of essential and nonessential amino acids.
- Fatty Acids: Reflecting the intake and metabolism of essential fats, crucial for inflammation balance and cell health.
- Oxidative Stress Markers: Identifying imbalances between free radicals and antioxidants, which can affect many health conditions.
- Nutrient & Toxic Elements: Assessing exposure to heavy metals like mercury and lead, while also evaluating essential minerals like magnesium and zinc.
Why Choose the NutrEval Test?
The NutrEval profile uses a systems-based approach to help clinicians develop personalized treatment plans for a wide range of health issues. With over 125 biomarkers evaluated through blood and urine samples, this test offers insights into a patient’s nutritional needs for over 40 key nutrients. This includes vitamins, minerals, antioxidants, essential fatty acids, amino acids, and digestive support elements.
NutrEval provides a clear, user-friendly report that includes:
- Personalized Nutrient Recommendations: Tailored to each patient’s test results, highlighting needs for vitamins, minerals, amino acids, and more.
- Functional Imbalance Scores: Helping guide therapy for issues like mitochondrial dysfunction, oxidative stress, toxic exposures, and fatty acid imbalances.
- Educational Resources: Detailed pages with nutrient function, deficiency causes, and dietary sources, making it easier for both clinicians and patients to understand their results.
- Biochemical Pathway Charts: Simplifying complex metabolic processes, enabling a better understanding of how specific biomarkers impact health.
When Should NutrEval Testing Be Considered?
Nutrient imbalances can have widespread effects on health and may contribute to a variety of chronic conditions. The NutrEval test is particularly beneficial for patients with conditions like:
- Mood Disorders: Imbalances in neurotransmitters and nutrient deficiencies are often linked to mood issues.
- Cardiovascular Disease: Assessing essential fatty acids and oxidative stress markers can provide insights into heart health.
- Diabetes and Insulin Resistance: NutrEval helps identify metabolic imbalances related to glucose regulation.
- Fatigue: Uncovering mitochondrial dysfunction or nutrient deficiencies that may be contributing to low energy levels.
- Cognitive Decline: Identifying nutrient needs for brain health and mental clarity.
- Athletic Performance: Supporting optimal nutrition for muscle recovery and overall performance.
- Malnutrition and Maldigestion: Helping address issues related to poor nutrient absorption or inadequate intake.
NutrEval Subpanels for Focused Assessments
For patients who may not require a full NutrEval profile, several subpanels are available to assess specific areas of concern. These include stand-alone assessments of organic acids, amino acids, fatty acids, and oxidative stress markers.
How Does NutrEval Work?
The NutrEval profile combines multiple assessment methods, including intracellular, extracellular, direct, and functional measurements. This holistic approach provides a more complete picture of a patient’s nutritional status, helping to uncover deficiencies that may not be evident through standard nutrient testing alone. By synthesizing the information from these various methods, NutrEval’s proprietary algorithm generates personalized nutrient recommendations based on the patient’s specific biomarker results.
Personalized Nutritional Support
The ultimate goal of the NutrEval profile is to help individuals achieve optimal health by addressing imbalances that might be hindering their wellness. By understanding each patient’s unique nutritional needs, healthcare providers can create targeted interventions that support better digestion, energy production, detoxification, and overall vitality.
For those seeking a thorough, individualized analysis of their nutritional status, the NutrEval test is an invaluable resource for improving long-term health and well-being.
Keywords: NutrEval, NutrEval test, functional nutrition, nutrient assessment, macronutrient test, micronutrient deficiencies, comprehensive health assessment, nutritional imbalances, oxidative stress, digestive function, mitochondrial health.
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Biomarkers included in this panel:
1-methylhistidine is derived from the dipeptide anserine (which consists of the amino acids 1-methylhistidine and beta-alanine). Anserine and its derivatives are associated with the consumption of poultry and fish. Both 1-methylhistidine and 3-methyl
Learn moreBoth 1-methylhistidine and 3-methylhistidine are histidine metabolites which have been proposed as markers of meat intake. Note that some confusion exists in the literature regarding the numbering of atoms in the imidazole ring of histidine &ndash
Learn moreAlpha-Amino-N-butyric acid (α-ANB), also known as alphaaminobutyric acid, is a nonessential amino acid derived from the catabolism of methionine, threonine, and serine. α-ANB is both formed and metabolized by reactions which require vi
Learn moreAlpha-aminoadipic acid (also known as 2-aminoadipic acid) is an intermediary biomarker of lysine and tryptophan metabolism. The further metabolism of alpha-aminoadipic acid to alpha-ketoadipic acid requires vitamin B6. Plasma alpha-aminoadipic aci
Learn moreAlanine is a nonessential amino acid. It is the second most abundant amino acid in circulation, after glutamine. It is found in many foods including eggs, meat, lentils, and fish. Alanine is involved in sugar metabolism for energy and is import
Learn moreArginine is found in all protein foods and is very abundant in seeds and nuts. It is considered a semi-essential amino acid during early development, infection/inflammation, or renal and/or intestinal impairment. It has many functions in the body inc
Learn moreAsparagine is a non-essential protein amino acid that is present in many fruits and vegetables including asparagus, from which it gets its name. Other dietary sources include meat, potatoes, eggs, nuts, and dairy. It can also be formed from aspart
Learn moreAspartic acid is a nonessential amino acid that plays roles in many important metabolic processes, such as energy production (citric acid cycle), hormone metabolism, CNS activation, and the urea cycle. It is found in many protein sources such as oyst
Learn moreβ-alanine is a breakdown product of carnosine and anserine, which are dipeptides from meat consumption. Although β-alanine’s properties are limited, its relationship to carnosine makes it important. Both have antioxidant properties. A
Learn moreBeta-aminoisobutyric acid (also known as 3-aminoisobutyric acid) is a non-protein amino acid formed by the catabolism of valine and the nucleotide thymine. It is further catabolized to methylmalonic acid semialdehyde and propionyl-CoA. Levels are
Learn moreCitrulline is an intermediate, nonprotein-forming amino acid in the urea cycle serving as a precursor to arginine. It derives its name from the watermelon (Citrullus vulgaris), where it was first isolated and identified. It is easily absorbed by t
Learn moreCysteine is a nonessential sulfur-containing amino acid. It is obtained from the diet and is also endogenously made from the intermediate amino acid cystathionine. Dietary cysteine sources include poultry, eggs, beef, and whole grains. This ami
Learn moreCystathionine is an intermediate dipeptide within the process of transsulfuration. Transsulfuration is the main route for irreversible homocysteine disposal, glutathione production, and energy. The initial step involves the enzyme cystathionine &b
Learn moreEthanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE
Learn moreGamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania. Although there are some dietary supplement and food sources for GABA (c
Learn moreGlutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the
Learn moreGlutamine is a nonessential amino acid and is the most abundant amino acid in the body. It is formed from glutamate using the enzyme glutamine synthetase. Approximately 80% of glutamine is found in the skeletal muscle, and this concentration is 30
Learn moreGlycine is a nonessential amino acid that is synthesized from choline, serine, hydroxyproline, and threonine. It has many important physiologic functions. It is one of three amino acids that make up glutathione. Glycine’s dietary sources inc
Learn moreHistidine is a semi-essential amino acid which is formed in the breakdown of carnosine. Red meat is a common source of carnosine, and therefore histadine. Other food sources include poultry, fish, nuts, seeds, and grains. Histidine and hista
Learn moreBranched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy). No
Learn moreBranched Chain Amino Acids (Isoleucine, Leucine, Valine) Isoleucine, leucine and valine are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat,
Learn moreLysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes. Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed f
Learn moreMethionine is an essential amino acid that plays an important role in the methylation cycle. Methionine is obtained from dietary intake or through homocysteine remethylation. Methionine’s dietary sources include eggs, fish, meats, Brazil nuts,
Learn moreOrnithine is an intermediate nonprotein-forming amino acid of the urea cycle. Arginine is converted to ornithine via the arginase enzyme, with urea as a byproduct. Ornithine combined with carbamoyl phosphate is then converted into citrulline via t
Learn morePhenylalanine is an essential amino acid found in most foods which contain protein such as meat, fish, lentils, vegetables, and dairy. Phenylalanine is the precursor to another amino acid, tyrosine. Because tyrosine is needed to form several
Learn morePhosphoethanolamine is an intermediate in the serineto-choline sequence. It is both a precursor and byproduct of phospholipid biosynthesis and breakdown. As a precursor to the phospholipid phosphatidylethanolamine, phosphoethanolamine plays a key rol
Learn morePhosphoserine is the phosphorylated ester of the amino acid serine. The addition of a phosphoryl group to an amino acid, or its removal, plays a role in cell signaling and metabolism. Phosphoserine is a byproduct of glycolysis and subsequent intermed
Learn moreProline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid. Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, pro
Learn moreSarcosine is an amino acid made within the methylation cycle when S-adenosylmethionine (SAM) is conjugated with glycine. It can also be made by catabolism of dimethylglycine (DMG). There are many dietary sources of sarcosine including eggs, legume
Learn moreSerine is found in soybeans, nuts, eggs, lentils, shellfish, and meats. Serine is a nonessential amino acid used in protein biosynthesis and can be derived from four possible sources: dietary intake, degradation of protein and phospholipids, biosy
Learn moreTaurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tis
Learn moreThreonine is a large neutral amino acid and a precursor for the amino acid glycine. Foods that contain relatively high amounts of threonine include cheeses (especially Swiss), meat, fish, poultry, seeds, walnuts, cashews, almonds and peanuts. Thre
Learn moreTryptophan is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP). 5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabo
Learn moreTyrosine is a conditionally essential amino acid which can come directly from the digestion of dietary protein. Common food sources include dairy, beans, whole grains, meat, and nuts. If intake is insufficient, tyrosine can be formed from the e
Learn moreUrea is a nontoxic byproduct of nitrogen (ammonia) detoxification. It is formed in the liver via the urea cycle and is the end product of protein metabolism. It is essentially a waste product with no physiological function.
Learn moreBranched Chain Amino Acids (Isoleucine, Leucine, Valine) Isoleucine, leucine and valine are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat,
Learn more