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IBD Expanded Panel (Inflammatory Bowel Disease)
A panel of serological markers that helps distinguish Crohn's disease from ulcerative colitis and flags Crohn's disease at higher risk of an aggressive course. Inflammatory bowel disease (IBD) is a chronic disorder of the lower gastrointestinal tract. It takes three main forms — Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC) — and affects roughly 0.3% of adults. Telling one form from another is often difficult and time-consuming, and the diagnostic gold standard, endoscopy with biopsy, is invasive. Blood-based serological markers offer a less invasive way to support the differential diagnosis and to signal disease likely to behave aggressively. The two long-established markers are anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear anti-neutrophil cytoplasmic antibodies (pANCA). ASCA are directed against a carbohydrate in the cell wall of baker's/brewer's yeast — a dietary and gut antigen rather than the body's own tissue — and are seen predominantly in Crohn's disease. pANCA is seen predominantly in ulcerative colitis.
View categoryIgG Allergens (14), Molds
The Allergen Profile, Mold (LabCorp) detects possible allergic responses to various substances in the environment and evaluates for hay fever, asthma, atopic eczema, and respiratory allergy.
View categoryIgG Subclass Deficiency
What Is the IgG Subclass Deficiency Panel? The IgG Subclass Deficiency Panel is a blood test that measures the levels of the four IgG (Immunoglobulin G) subclasses: IgG1 IgG2 IgG3 IgG4 These subclasses are all part of the IgG antibody family, which plays a crucial role in your immune system's ability to recognize and fight off bacteria, viruses, and other pathogens. While total IgG may appear normal, an individual may still be deficient in one or more subclasses—this is known as an IgG subclass deficiency. Why Is This Test Ordered? This panel is typically ordered if you: Have frequent or recurrent infections, especially of the sinuses, lungs, or ears Show signs of a weakened immune system Have a normal total IgG level but suspected immune dysfunction Are being evaluated for a primary immunodeficiency disorder (PID) Are being monitored for certain autoimmune or inflammatory conditions What Each IgG Subclass Does IgG1: The most abundant subclass, important for response to protein antigens (like tetanus or diphtheria).
View categoryIgG Yeasts Allergy Test
Immunoglobulin G (IgG) food testing is a useful guide for structuring elimination diets for patients with many chronic conditions. Individuals with neurological, gastrointestinal, movement, and behavioral disorders often suffer from IgG food sensitivities. People may continue to eat offending foods unaware of their potential adverse effects. Symptoms associated with food sensitivities may occur hours or days after the offending food was eaten because IgG food antibodies remain for a much longer time than traditional IgE antibodies. As immunological reactions, IgE food allergy causes the release of histamine, producing an immediate hypersensitivity reaction, in which symptoms appear within minutes or hours. In contrast, food sensitivity is a non-IgE allergy characterized by the measurement of IgG antibodies specific to antigenic food proteins. This IgG food allergy is a delayed hypersensitivity reaction in which symptoms appear anywhere from hours to days after eating the offending food.
View categoryILDdx Profile (RDL)
This test is used for evaluating Interstitial Lung Disease (ILD) associated with various autoimmune disorders such as Systemic Sclerosis (SS), Sjögren's Syndrome (SjS), Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathies (IIM), and ANCA-Associated Vasculitis (AAV). Identifying an underlying autoimmune condition in ILD patients is crucial for guiding therapeutic decisions and significantly influences prognosis.
View categoryImmune System
The Immune System category includes biomarkers that help evaluate how well your body identifies, responds to, and regulates threats such as infections, inflammation, and autoimmune activity. These tests measure different arms of the immune system, including antibodies, inflammatory proteins, complement activity, and clotting-related markers influenced by immune responses. This category covers a broad range of clinical insights—such as the presence of autoantibodies seen in autoimmune disorders, markers of joint or tissue inflammation, immune-mediated neuromuscular conditions, and tests that help assess abnormal clotting associated with immune dysfunction. Together, these biomarkers assist in detecting immune activation, identifying autoimmune diseases, monitoring chronic inflammatory conditions, and guiding treatment decisions. Whether assessing unexplained symptoms, tracking an autoimmune diagnosis, or evaluating the body’s response to infections, the Immune System category provides a comprehensive view of the body’s defense and regulatory mechanisms.
View categoryImmunoCAP Specific IgE Blood Test (Allergy Testing by Quest Diagnostics)
The ImmunoCAP Specific IgE blood test, offered by Quest Diagnostics, is a highly specialized diagnostic tool used to detect specific IgE antibodies in the blood, which are associated with allergic reactions. This test is pivotal in the accurate identification of allergies to substances such as foods, pollens, molds, animal dander, and insect stings. Utilizing cutting-edge technology, the ImmunoCAP® system is renowned for its precision and sensitivity, making it a preferred choice among healthcare professionals for allergy testing. By measuring the concentration of specific IgE antibodies, the test provides valuable information that can assist in the diagnosis and management of allergic conditions, leading to personalized treatment plans and improved patient care. This detailed approach to allergy testing is integral in understanding individual allergic responses and in devising strategies for effective management and mitigation of allergy symptoms.
View categoryImmunodeficiency Panel
IMMUNODEF.PANEL(T/B/NK)
View categoryImmunoserology of Lyme
What is Immunoserology of Lyme? The Immunoserology of Lyme panel is a serum-based test that uses advanced ELISA methodology to detect both active and chronic Lyme disease, including complications such as Lyme arthritis and neuroborreliosis. This panel measures IgM and IgG antibodies against Borrelia burgdorferi and its subspecies (B. afzelii, B. garinii, B. miyamotoi), as well as potential tick-borne co-infections like Babesia, Bartonella, and Ehrlichia. By analyzing antibodies to multiple Borrelia antigens—such as Outer Surface Proteins (OspA, OspB, OspC, OspE), Variable Major Protein (VMP), and Leukocyte Function Associated Antigen (LFA)—the test provides a more precise and reliable diagnosis than standard Lyme assays. Why Accurate Lyme Testing Matters Lyme disease often mimics autoimmune or neurological conditions, making misdiagnosis common. False positives can lead to unnecessary treatment and side effects. False negatives may delay care, increasing the risk of arthritis, meningitis, or long-term neurological complications.
View categoryInfectious Disease Profile
Includes Interpretation Tips, Risk Insights, and Treatment Guidance Updated: July 13, 2025 (BD) The Infectious Disease Profile includes a range of diagnostic biomarkers used to detect and monitor infections caused by viruses, bacteria, or other pathogens. A key focus of this profile is hepatitis, an inflammation of the liver that can lead to serious health outcomes if left untreated. What Is Hepatitis? Hepatitis refers to liver inflammation, which can be acute (short-term) or chronic (long-term). While some cases resolve on their own, others progress to fibrosis (liver scarring), cirrhosis (permanent liver damage), or even liver cancer. Common Causes of Hepatitis: Viral infections (the most common cause worldwide) Toxic substances such as alcohol or certain medications Autoimmune diseases Other infections not directly linked to hepatitis viruses Types of Hepatitis Viruses: There are five main hepatitis viruses—Hepatitis A, B, C, D, and E—each with unique modes of transmission, severity, and long-term effects: Type Transmission Risk of Chronic Disease Common in Hepatitis A (HAV)
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