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Lab panels and marker groups — each with the biomarkers that define it.

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35 markers

Daily Free Cortisol and Cortisone + Metabolites (Urine) - DUTCH

This section of the DUTCH test evaluates your body’s daily stress hormone patterns by measuring free cortisol, free cortisone, and their metabolites. It answers five key questions: What is the overall free cortisol pattern across the day? What is the total free cortisol for the day? What is your Cortisol Awakening Response (CAR)? What is the total amount of cortisol metabolites? Does your body prefer to produce active cortisol or inactive cortisone? Understanding the Cortisol Awakening Response (CAR) The Cortisol Awakening Response reflects how sharply cortisol rises in the first 30–40 minutes after waking. Normal pattern: Cortisol peaks shortly after waking, then gradually declines through the day, reaching its lowest point at night. CAR calculation: The difference between your waking cortisol sample and the one collected 30–40 minutes later. Why it matters: Low or flat CAR may suggest low HPA axis activity (underactive stress response) and can be linked to fatigue, burnout, sleep disorders, PTSD, and certain chronic illnesses.

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1 marker

DetoxiGenomic Profile and a la carte SNPs

The DetoxiGenomic® Profile and a la carte SNPs are designed to assess genetic risks for chronic diseases. According to the CDC, precision medicine, also known as personalized medicine, tailors patient care based on genetics, lifestyle, and environmental factors. Single Nucleotide Polymorphisms (SNPs) are genetic variants that can predispose patients to various chronic diseases. By testing for these SNPs, clinicians can identify genetic predispositions and customize treatments. Everyone has SNPs, which are common and generally not as severe as genetic mutations. SNPs subtly reduce cellular functions, impacting overall quality of life. Genomic testing helps identify hidden gene polymorphisms that may lead to chronic diseases. Many people mistakenly believe that having a SNP means they will develop the associated disease. However, most genes can be influenced by environmental, dietary, and lifestyle factors. Genotypic SNP testing can prompt monitoring of associated biomarkers, such as closely watching homocysteine levels in patients with MTHFR polymorphisms.

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11 markers

DUTCH (male)

The DUTCH test is a urine steroid hormone test that measures hormones and hormone metabolites from a dried urine sample.

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