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Optimal range: 0.023 - 0.085 Units
Absolute Reticulocyte Count (ARC) is a critical blood test used to assess the bone marrow's ability to produce red blood cells (RBCs), essential for diagnosing and managing various hematological conditions. Reticulocytes are immature red blood cells, and their absolute count indicates the rate of RBC production. This test is particularly vital for patients with anemia or those undergoing treatments like chemotherapy, as it helps determine whether the bone marrow is responding adequately.
Optimal range: 109 - 897 cells/mcL
The Absolute T-Suppressor Cells marker is an important measurement that gives doctors a closer look at a specific part of your immune system. T-suppressor cells, also known as CD8+ cells, play a critical role in managing and regulating your body's immune response. These cells are like the body's own regulatory officials, working to calm the immune system down and prevent it from overreacting, which can be just as harmful as underreacting. The "absolute" part of the marker's name refers to the actual count of these T-suppressor cells in a sample of your blood, giving a clear picture of how many are present to perform their crucial function.
Reference range: LOW, MEDIUM, HIGH
Absorption markers on the Boston Heart Cholesterol Balance® test provide crucial insights into how effectively cholesterol is being absorbed in the body. These markers include beta-sitosterol, campesterol, and cholestanol, which are key indicators of cholesterol absorption from the intestine. Beta-sitosterol and campesterol, both plant sterols, are absorbed into intestinal cells and serve as excellent indicators of cholesterol absorption efficiency. Cholestanol, another absorption marker, reflects the conversion of cholesterol into bile acid chenodoxycholate. By measuring these markers in plasma or serum, the test can predict a patient's response to cholesterol-lowering treatments such as statins and ezetimibe. This information helps healthcare providers tailor treatment plans to optimize cholesterol management and improve cardiovascular health outcomes.
Optimal range: 0.1 - 0.8 Ratio
AC/FC, which stands for Acylcarnitine to Free Carnitine ratio, is an important marker used in the assessment of metabolic health, particularly in diagnosing and managing metabolic disorders related to fatty acid metabolism. Carnitine is a vital molecule that helps transport fatty acids into the mitochondria, the energy powerhouses of cells, where they are broken down to produce energy. The AC/FC ratio reflects the balance between acylcarnitines, which are fatty acids bound to carnitine, and free carnitine, which is available for further transport activities. This ratio can provide insights into how efficiently the body is processing and utilizing fatty acids.
Optimal range: 0 - 80 Units
The IBD Expanded Panel test offers three novel markers:
- antichitobioside IgA (ACCA),
- antilaminaribioside IgG (ALCA),
- antimannobioside IgG (AMCA),
together with anti-Saccharomyces cerevisiae IgG (gASCA) and pANCA.
Optimal range: 14 - 82 U/L
The ACE (Angiotensin-converting enzyme) test is a blood test that measures the amount of ACE, an enzyme that plays a role in blood pressure regulation. Higher levels of ACE can be an indicator of sarcoidosis, a complex disease with an unclear cause that typically impacts the lungs and can also involve various organs such as the eyes, skin, nerves, liver, and heart.
Sarcoidosis is characterized by the formation of granulomas—clustered masses of immune cells, inflammatory cells, and fibrous tissue. These granulomas can alter the normal structure of tissues, potentially leading to organ damage and inflammation if they are numerous enough. The presence of these granulomas, especially around their outer edges, can lead to elevated ACE levels in the blood.
Optimal range: 44.5 - 72.4 %
Acetate is the most abundant SCFA in the colon and makes up more than half of the total SCFA detected in feces. These beneficial SCFA have anti-inflammatory properties, provide energy to nourish the colonic epithelial cells and intestinal microbiota, and exert numerous positive effects on gut homeostasis.
Optimal range: 50 - 72 %
Acetate is the most abundant SCFA in the colon and makes up more than half of the total SCFA detected in feces. These beneficial SCFA have anti-inflammatory properties, provide energy to nourish the colonic epithelial cells and intestinal microbiota, and exert numerous positive effects on gut homeostasis.
Optimal range: 60.2 - 72.7 %
Acetic Acid can inhibit the accumulation of body fat and hepatic lipids without altering food consumption. It suppresses body fat accumulation by upregulating genes necessary for fatty-acid oxidation and mitochondrial processing. It has been found to have an inhibitory effect on the conversion of glucose to fatty acids in the liver. It has also been suggested as a promising compound for improving obesity and obesity-linked type 2 diabetes.
Optimal range: 48.1 - 69.2 %
Acetate is the most abundant SCFA in the colon and makes up more than half of the total SCFA detected in feces. These beneficial SCFA have anti-inflammatory properties, provide energy to nourish the colonic epithelial cells and intestinal microbiota, and exert numerous positive effects on gut homeostasis.
Optimal range: 0 - 620 rpkm
Acetate is the most abundant SCFA in the colon and makes up more than half of the total SCFA detected in feces. These beneficial SCFA have anti-inflammatory properties, provide energy to nourish the colonic epithelial cells and intestinal microbiota, and exert numerous positive effects on gut homeostasis.
Optimal range: 44.5 - 72.4 %
Acetate is the most abundant SCFA in the colon and makes up more than half of the total SCFA detected in feces. These beneficial SCFA have anti-inflammatory properties, provide energy to nourish the colonic epithelial cells and intestinal microbiota, and exert numerous positive effects on gut homeostasis.
Optimal range: 15.848 - 34.164 Healthy Relative Abundance IQR (%)
Acetate is another SCFA produced by gut bacteria through the fermentation of prebiotic fibers like inulin and GOS or unabsorbed peptides and fats. Gut-derived acetate production is tightly regulated within the microbiome and determined by the presence of prebiotic fiber and the balance between saccharolytic and proteolytic fermentation. Acetate is used for cholesterol synthesis and lipogenesis but can also be utilized by muscle tissue. Additionally, some gut bacteria like Roseburia spp and Faecalibacterium prausnitzii can convert acetate into butyrate. Excessive acetate production combined with insufficient butyrate production can lead to fat gain, particularly around the liver.
Optimal range: 5 - 30 mcg/mL
The biomarker Acetoacetate, measured in serum or plasma (S/P) is a key component in the evaluation of ketone body levels within the human body. Acetoacetate is one of the three primary ketone bodies, alongside beta-hydroxybutyrate and acetone, produced during the process of ketogenesis, which occurs primarily in the mitochondria of liver cells. This metabolic process is triggered under conditions where glucose availability is insufficient to meet the body's energy demands, such as during prolonged fasting, carbohydrate-restricted diets, or uncontrolled diabetes mellitus.
Optimal range: 0 - 10 mmol/mol creatinine
Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Optimal range: 0 - 0 mmol/mol creatinine
Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Optimal range: 0 - 10 mmol/mol creatinine
Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Optimal range: 0 - 10 mmol/mol creatinine
Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.
Optimal range: 0 - 9.6 mmol/mol
Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.