Both 1-methylhistidine and 3-methylhistidine are histidine metabolites which have been proposed as markers of meat intake.

Note that some confusion exists in the literature regarding the numbering of atoms in the imidazole ring of histidine – 1 versus 3 – and thus, there is caution with interpretation and clinical significance of these two markers.

3-methylhistidine is a constituent of actin and myosin, the contractile proteins of skeletal muscles. Urinary excretion of 3-methylhistidine may be a result of muscle breakdown or consumption of meat fibers. Unlike 1-methylhistidine, 3-methylhistidine has been shown to increase in fasting states indicating catabolism of muscle tissue. Therefore, this marker is more variable with regards to animal protein consumption.

Both 1-methylhistidine and 3-methylhistidine are histidine metabolites which have been proposed as markers of meat intake. Note that some confusion exists in the literature regarding the numbering of atoms in the imidazole ring of histidine – 1 versus 3 – and thus, there is caution with interpretation and clinical significance of these two markers.

3-methylhistidine is a constituent of actin and myosin, the contractile proteins of skeletal muscles. Urinary excretion of 3-methylhistidine may be a result of muscle breakdown or consumption of meat fibers. Unlike 1-methylhistidine, 3-methylhistidine has been shown to increase in fasting states indicating catabolism of muscle tissue. Therefore, this marker is more variable with regards to animal protein consumption.

3-Methylhistidine is an amino acid which is excreted in human urine.

The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

3-Methylhistidine is an amino acid which is excreted in human urine.

The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

3-Methylhistidine is an amino acid which is excreted in human urine.

The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

3-O-Methyldopa (3-OMD) is a compound that emerges in the context of diagnosing and monitoring various medical conditions, particularly those related to neurological disorders such as Parkinson's disease. It's essential to understand that 3-OMD is closely related to L-DOPA, a medication widely used in the treatment of Parkinson's disease. In patients receiving L-DOPA therapy, 3-OMD is produced as a metabolite - a substance created during the breakdown and conversion of the drug within the body. 

If the concentraton of 3-O-methyldopa in plasma is within the reference range, it demonstrates that the individual does not have aromatc L-amino acid decarboxylase (AADC) defciency.

3-Oh-Butyric Acid is a metabolic marker of blood sugar utilization and insulin function.

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

3-Oxoglutaric acid is a simple carboxylic acid and a key intermediate in the Krebs cycle, which has also been identified as a microbial metabolite. Its presence is often linked to the overgrowth of harmful or dysbiotic gut flora, such as Candida albicans. Research has shown that children with autism tend to have lower levels of 3-oxoglutaric acid, potentially due to increased uptake of this compound across the blood-brain barrier. Elevated levels of 3-oxoglutaric acid may suggest a yeast overgrowth in the gastrointestinal (GI) tract. It may be beneficial to consider further testing, such as a Gut Zoomer panel and fungal antibodies test, to assess the extent of dysbiosis and identify the root cause. A gut restorative protocol, which could include high-potency multi-strain probiotics, prescription or natural antifungals, and other targeted gut support, may be recommended to help restore microbial balance and improve overall gut health.

Pyrethrins are widely used as insecticides. Exposure during pregnancy doubles the likelihood of autism. Pyrethrins may affect neurological development, disrupt hormones, induce cancer, and suppress the immune system.