The cashew tree, belonging to the plant family Anacardiaceae, grows in the tropical climate and produces cashew apples and cashew seeds. The cashew seed, which is mostly just referred to as cashew, is widely consumed either on its own, raw or roasted, or used in a variety of recipes.

The presence of antibodies to Casomorphin is an indication of food immune reactivity. The offending food and its known cross-reactive foods should be eliminated from the diet. Casomorphin is known to modulate the mucosa of the intestinal lining. If the mucosa is damaged, Casomorphin and other ingested peptides can more easily penetrate the intestinal barrier. As an opioid peptide, Casomorphin, once in the blood stream, is capable of disrupting the blood-brain barrier and interfering with the neurotransmitter messaging system.

Antibodies against Casomorphin can identify a cause of behavioral and cognitive problems.

Known Cross-Reactions: Cerebellar, Gliadin

The presence of salivary antibodies to Casomorphin is an indication of loss of mucosal tolerance and the onset of food immune reactivity. The production of antibodies to Casomorphin may be indicative of a lack of the enzyme dipeptidyl peptidase (DPPIV). The offending food and its known cross-reactive foods should be eliminated from the diet. Casomorphin is known to modulate the mucosa of the intestinal lining. If the mucosa is damaged, Casomorphin and other ingested peptides can more easily penetrate the intestinal barrier. As an opioid peptide, Casomorphin, once in the blood stream, is capable of disrupting the blood-brain barrier and interfering with the neurotransmitter messaging system. Antibodies against Casomorphin can identify a cause of behavioral and cognitive problems.

Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.

Catecholamines are a group of similar hormones released into the bloodstream in response to physical or emotional stress.

The primary catecholamines are:

• Dopamine,
• Epinephrine (adrenaline), and
• Norepinephrine.

Catenibacterium, a lesser-known but significant genus of bacteria in the gut microbiome, is gaining attention in gut health assessments, including comprehensive gut tests. These bacteria are part of the natural flora of the human gastrointestinal tract and play a role in the complex ecosystem of the gut. While not as extensively studied as other genera like Lactobacillus or Bifidobacterium, Catenibacterium has been implicated in various functions that are crucial for maintaining gut health and overall well-being.

Consumption of a Western diet has been shown to increase Catenibacterium mitsuokai in the human gut microbiota.

Catenibacterium mitsuokai ferments glucose, mannose, galactose, fructose, sucrose, maltose, cellobiose, lactose and salicin in the production of lactic acid, acetic acid as well as iso-butyric acid.

The presence of Catenibacterium mitsuokai has been positively associated with obesity-related insulin resistance.

CCL3, also known as Macrophage Inflammatory Protein-1 alpha (MIP-1α), is a chemokine protein that plays a critical role in the immune response and inflammation. Chemokines are small proteins that act as signaling molecules, attracting and directing immune cells to sites of infection, injury, or inflammation within the body.

CCL3 is produced by various cell types, including macrophages, monocytes, and dendritic cells. It is part of the CC (or beta) chemokine family, which indicates the presence of two adjacent cysteine residues near the amino terminus of the protein. CCL3 interacts with specific receptors on the surface of target cells, primarily the CCR1, CCR4, and CCR5 receptors.

CCL4 is a chemoattractant for critical immune regulatory cells such as monocytes/macrophages, T-lymphocytes, natural killer cells and dendritic cells.

CCL4 is produced by monocytes, T/B lymphocytes, neutrophils, fibroblasts and endothelial/epithelial cells. CCL4 expression by neutrophils contributes to inflammation by recruiting other leukocytes at site(s) of inflammation which results in resolution of inflammation by macrophage-mediated efferocytosis or development of chronic inflammation.

T-Cell-Specific Protein RANTES is chemotactic for T-cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. It also activates the release of proteins from eosinophils such as eosinophilic cationic protein. It changes the density of eosinophils and makes them hypodense, which is thought to represent a state of generalized cell activation and is associated most often with diseases such as asthma and allergic rhinitis.

Anti-cyclic citrullinated peptide (anti-CCP) is an antibody present in most rheumatoid arthritis patients.

CD19 is a protein that serves as a cell surface marker found on B-lymphocytes (B-cells), which are a type of white blood cell crucial to the adaptive immune system. As part of the B-cell receptor complex, CD19 functions as a co-receptor that enhances the sensitivity and response of B-cells to antigens. This protein plays a vital role in B-cell development, activation, proliferation, and differentiation.

CD2 is a type I transmembrane glycoprotein that is expressed on the surface of T cells, natural killer cells, thymocytes, and dendritic cells. The CD2 protein is also a costimulatory receptor that plays a role in T cell activation and signaling.