Easy Interpretation of your Lyme results:
IgM
CDC Criteria - 1 Positive - VlsE1, C6 peptide, or WCS AND 2 of the following 3 antigens are Positive -- 23-25, 39, 41
Alternative Criteria - 1 Positive/Borderline - VlsE1, C6 peptide, or WCS AND 2 of the following 6 antigens are Positive/Borderline -- 23-25, 31, 34, 39, 41, 83-93
IgG
CDC Criteria - 1 Positive - VlsE1, C6 peptide, or WCS AND 5 of the following 10 antigens are Positive -- 18, 23-25, 28, 30, 39, 41, 45, 58, 66, 83-93
Alternative Criteria - 1 Positive/Borderline - VlsE1, C6 peptide, or WCS AND 2 of the following 12 antigens are Positive/Borderline -- 18, 23-25, 28, 30, 31, 34, 39, 41, 45, 58, 66, 83-93
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Borreliella burgdorferi is one of the pathogens of the Borreliella burgdorferi sensu lato complex causing Lyme disease. Lyme disease is a zoonotic, vector-borne disease transmitted by the Ixodes tick. Clinical presentation of Lyme disease is known for the characteristic bull's-eye rash (also known as erythema migrans) but can also include myocarditis, cardiomyopathy, arrythmia, arthritis, arthralgia, meningitis, neuropathies, and facial nerve palsy depending on the stage of infection.
Outer surface protein A (OspA) is one of the major proteins in the outer membrane of this B. burgdorferi. A vaccine based OspA was approved by the FDA in 1998. Individuals vaccinated subcutaneously showed approximately 76% protection agains B. burgdorferi infection after receiving three vaccine doses; however, the human vaccine was removed from the market later.
Borrelia burgdorferi p31 (OspA) - IgM
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