Borreliella burgdorferi is one of the pathogens of the Borreliella burgdorferi sensu lato complex causing Lyme disease. Lyme disease is a zoonotic, vector-borne disease transmitted by the Ixodes tick. Clinical presentation of Lyme disease is known for the characteristic bull's-eye rash (also known as erythema migrans) but can also include myocarditis, cardiomyopathy, arrythmia, arthritis, arthralgia, meningitis, neuropathies, and facial nerve palsy depending on the stage of infection.
OspC is the second most-commonly targeted antigen in diagnostic testing and has an important role in transmission of Lyme disease-associated Borrelia from the tick vector to the mammalian host.
Borrelia burgdorferi p23-25 (OspC)
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