Borrelia burgdorferi C6 peptide - IgM

By CDC criteria Lyme IgM is reported positive if VlsE1 or C6 peptide or WCS (Whole cell sonicate) is positive and two of the following three antigens are positive:

23-25kDa,

39kDa

and 41kDa.

In the alternate criteria IgM is reported positive if VlsE1 or C6 peptide or WCS (Whole cell sonicate) is borderline or positive and any two of the following antigens are borderline or positive:

23-25kDa,

31kDa,

34kDa,

39kDa,

41kDa

and 83-93kDa.

Borreliella burgdorferi is one of the pathogens of the Borreliella burgdorferi sensu lato complex causing Lyme disease. Lyme disease is a zoonotic, vector-borne disease transmitted by the Ixodes tick. Clinical presentation of Lyme disease is known for the characteristic bull's-eye rash (also known as erythema migrans) but can also include myocarditis, cardiomyopathy, arrythmia, arthritis, arthralgia, meningitis, neuropathies, and facial nerve palsy depending on the stage of infection.