Bartonella henselae 17 kDa - IgM

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What is Bartonella henselae 17 kDa – IgM?

Bartonella henselae is a bacterium best known for causing cat scratch disease, but it is also associated with more complex, chronic, or systemic infections—especially in people with weakened immune systems or in cases of vector-borne illness. It is primarily transmitted through scratches or bites from cats, but can also be spread via fleas, ticks, or other insect vectors.

The 17 kDa – IgM test detects IgM antibodies produced in response to the 17-kilodalton outer membrane protein of Bartonella henselae. IgM is the first type of antibody the immune system produces during an infection, typically appearing within 1–2 weeks after exposure.

What does it mean if your Bartonella henselae 17 kDa - IgM result is too high?

What Does a Positive or Elevated IgM Result Mean?

A positive or elevated IgM result for Bartonella henselae 17 kDa suggests:

  • A recent or active Bartonella infection

  • The immune system is mounting an early-stage response to the bacterium

  • You may be currently experiencing symptoms related to Bartonella infection

Because IgM reflects early immune activity, this result is most useful for identifying acute or newly acquired infections.

Common Symptoms of Bartonella henselae Infection

Symptoms may vary depending on the individual and the type of infection. Common presentations include:

  • Swollen lymph nodes (especially near the site of a scratch or bite)

  • Fever

  • Fatigue

  • Headache

  • Muscle or joint pain

  • Eye involvement (neuroretinitis or conjunctivitis)

  • Neurologic symptoms in more severe or chronic cases (e.g., confusion, irritability, seizures)

Chronic or systemic Bartonella infections may be more difficult to diagnose and can mimic other conditions.


Next Steps

  • Consult your healthcare provider to interpret this result in the context of your symptoms, exposure risks (e.g., recent contact with cats or flea/tick exposure), and overall health.

  • Consider additional testing, such as IgG, PCR, or a Bartonella enrichment culture, especially if symptoms are ongoing or unclear.

  • Treatment may involve antibiotics such as azithromycin or doxycycline, depending on the severity and type of symptoms.


Summary

The Bartonella henselae 17 kDa – IgM test detects early immune response to a bacterium that can cause cat scratch disease and other systemic infections. A medium or positive result may indicate a recent infection and should be carefully evaluated in combination with symptoms and additional testing. Early diagnosis and treatment can help reduce complications, particularly in people with persistent or atypical symptoms.

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