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Optimal range: 16 - 63 pg/mL
Aldosterone is a mineralcoritcoid and a hormone. It allows the transport of sodium across the cell membrane. This is especially important in the kidney (distal tubule). Because of its function, aldosterone is important in blood pressure regulation and also for the volume of blood found in the blood vessels. Potassium is an antagonist to sodium. If potassium is high, sodium levels will be low. When potassium is found high in the plasma of the blood, the adrenals step in and synthesize aldosterone. The synthesis of aldosterone is taken care of in the body primarily by the renin-angiotensin system.
Optimal range: 0 - 2.1 mcg/g Creat.
Aldosterone is a mineralcoritcoid and a hormone. It allows the transport of sodium across the cell membrane. Aldosterone is important in blood pressure regulation and also for the volume of blood found in the blood vessels.
Optimal range: 0.9 - 28.9 Ratio
The aldosterone-renin ratio (ARR), also known as the aldosterone plasma renin activity (PRA) ratio, is a critical diagnostic tool used in the evaluation of primary aldosteronism, a condition characterized by excessive production of the hormone aldosterone by the adrenal glands.
Reference range: -3, -2, -1, 0, +1, +2, +3
- Alistipes does not contribute significantly to short chain fatty acid production.
- A diet rich in animal protein and fat increases the abundance of Alistipes.
- High abundance of Alistipes was identified as a possible predictor of successful weight loss.
- Alistipes may positively correlate with depression.
Reference range: -3, -2, -1, 0, +1, +2, +3
Alistipes does not contribute significantly to short chain fatty acid production. A diet rich in animal protein and fat increases the abundance of Alistipes. High abundance of Alistipes was identified as a possible predictor of successful weight loss. Increased abundance of Alistipes has been correlated with a greater frequency of pain in pediatric irritable bowel syndrome patients.
Optimal range: 6 - 22.7 ug/L
Bone-specific alkaline phosphatase (BAP or BSAP) is an enzyme produced primarily by osteoblasts, the cells responsible for building new bone. It is a specific isoenzyme of the broader alkaline phosphatase (ALP) family, which includes enzymes from the liver, intestines, kidneys, and placenta.
Unlike total ALP, which reflects contributions from various organs, BAP directly reflects bone metabolism. Measuring BAP levels in the blood provides a more accurate picture of bone turnover, which is critical in diagnosing and monitoring bone-related conditions.
Optimal range: 44 - 121 U/L , 44 - 121 IU/L
Alkaline phosphatase (ALP) is an enzyme found in your liver, bones, and bile ducts. It plays an important role in bone formation and liver function. The ALP blood test helps evaluate conditions affecting the liver, bile ducts, or bones.
High ALP levels may suggest bile duct blockage, liver disease, vitamin D deficiency, or increased bone turnover (such as during growth or bone healing). Low ALP may be related to nutrient deficiencies, thyroid issues, or rare genetic conditions affecting bone strength.
ALP is usually interpreted alongside other tests like GGT, AST, ALT, vitamin D, and calcium to help identify the cause of abnormal results.
Optimal range: 105 - 412 ug/g Creatinine
Allo-Tetrahydrocorticosterone (5α-THB) is a significant biomarker in dried urine panel analysis, offering vital insights into the body's hormonal balance and stress response. As a metabolite of cortisol, 5α-THB is crucial in understanding the body's glucocorticoid activity, a fundamental aspect of the stress response mechanism. Cortisol, produced by the adrenal glands, is known as the "stress hormone," playing a pivotal role in various physiological processes including metabolism regulation, immune response modulation, and stress adaptation. In the metabolic pathway, cortisol is reduced to tetrahydrocortisol (THF) and subsequently transformed into 5α-THB. This conversion is catalyzed by the enzyme 5α-reductase, which also participates in other critical physiological processes such as androgen metabolism.
Optimal range: 73 - 192 ng/mg CR
Metabolized cortisol is the sum of a-tetrahydrocortisol (a-THF), b-tetrahydrocortisol (b-THF), and b-tetrahydrocortisone (b-THE). They are a good indication of the total cortisol output from the adrenal gland or clearance out the body.
Optimal range: 443 - 1651 ug/g Creatinine
LEARN MOREOptimal range: 0 - 0 micromol/24 hr
This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.
Optimal range: 57 - 370 nmol/dL (SG)
This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.
Optimal range: 38 - 331 nmol/dL (SG)
This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.
Optimal range: 0 - 3.2 umol/L
Allo-isoleucine is nearly undetectable in individuals not affected by maple-syrup urine disease (MSUD). Accordingly, its presence is diagnostic for MSUD, and its absence is sufficient to rule-out MSUD.
Optimal range: 0.1 - 13.5 umol/g Cr
Allo-isoleucine is nearly undetectable in individuals not affected by maple-syrup urine disease (MSUD). Accordingly, its presence is diagnostic for MSUD, and its absence is sufficient to rule-out MSUD.
Optimal range: 14.65 - 76.71 µg/g creatinine
Allopregnanediol, or 5a-pregnane-3a,20a-diol, is an endogenous metabolite of progesterone and allopregnanolone and an isomer of pregnanediol.
Optimal range: 1.38 - 6.75 ug/g Cr
Allopregnanediol, or 5a-pregnane-3a,20a-diol, is an endogenous metabolite of progesterone and allopregnanolone and an isomer of pregnanediol. Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans. It belongs to a group of steroid hormones called the progestogens and is the major progestogen in the body. Progesterone has a variety of important functions in the body. It is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. In addition to its role as a natural hormone, progesterone is used as a medication, for instance in menopausal hormone therapy.
Optimal range: 2.23 - 14.87 µg/g creatinine
Allopregnanolone, also known as brexanolone, is a medication and a naturally produced steroid that acts on the brain. Allopregnanolone possesses a wide variety of effects, including, in no particular order, antidepressant, anxiolytic, stress-reducing, rewarding, prosocial, antiaggressive, prosexual, sedative, pro-sleep, cognitive, memory-impairment, analgesic, anesthetic, anticonvulsant, neuroprotective, and neurogenic effects.
Optimal range: 0.8 - 6.4 ng/mg Creat/Day
Allopregnanolone is a potent neuroactive steroid capable of binding the GABA-A receptor often leading to sedative and anxiolytic action. The calming action of allopregnanolone is often seen with orally supplemented progesterone, as the liver metabolizes a large portion of oral progesterone to the neuroactive steroid allopregnanolone.
Optimal range: 0.32 - 1.2 ug/g Cr
Allopregnanolone, a neurosteroid of growing interest in male health. This metabolite of progesterone plays a crucial role in modulating brain function, particularly influencing mood, stress response, and cognitive processes. In men, allopregnanolone levels are essential for maintaining neurological and psychological well-being. Abnormal levels of allopregnanolone can be indicative of various health issues, ranging from mood disorders to neurodegenerative diseases. The inclusion of allopregnanolone in ZRT's urinary neurotransmitter panel allows for a more comprehensive assessment of a patient's neuroendocrine status, contributing to a deeper understanding of the complex interplay between hormones and neurotransmitters in men's health.