In contrast to most other body secretions examined for the purpose of diagnosis or follow-up of treatment, the ejaculate is a heterogeneous mixture of secretions that does not exist within the body before being expelled. The ejaculate is produced from a concentrated suspension of spermatozoa, stored in the paired epididymides, mixed with, and diluted by, primarily the prostatic fluid in the urethra, followed by the emptying of the secretion of the seminal vesicles. Thus, the sequential ejaculate fractions are not equally composed. Comparison of pre- and post-vasectomy ejaculate volume reveals that about 90% of the volume is composed of secretions from the accessory organs, mainly the prostate and seminal vesicles, with minor contributions from the bulbourethral (Cowper’s) glands and epididymides.
There is some evidence that the total volume and the content of spermatozoa of ejaculates vary depending on the circumstances under which the ejaculate is produced. Ejaculates produced by masturbation and collected in containers in a room near the laboratory can result in lower yield than those recovered from nonspermicidal condoms used during intercourse at home. This difference may reflect a different level and duration of sexual arousal, since the time spent producing a sample by masturbation also influences the ejaculate volume and contents.
Under given conditions of collection, ejaculate characteristics depend on factors that usually cannot be modified, such as sperm production by the testes, accessory organ secretions and recent (particularly febrile) illness, as well as other factors, such as ejaculation abstinence, that should be recorded and considered in interpreting the results.
Key patient factors influencing the ejaculate will include:
→ The size of the testicles, which influences the total number of spermatozoa produced per day and thereby indirectly output per ejaculate. Testicular size reflects the level of spermatogenic capacity, which is also related to sperm morphology.
→ Endocrine status
→ Medications the man is taking. For instance, the transport of spermatozoa from the epididymides to the urethra depends on the activation of alpha-1 receptors in smooth muscle cells in the vasa deferentia. Treatment with alpha-blockers (anti-hypertensive drugs and symptomatic treatment of prostate hypertrophy) or selective serotonin reuptake inhibitor (SSRI) antidepressants (e.g. sertraline, fluoxetine, amitriptyline) can inhibit vas deferens motility and also accessory sex gland emptying.
→ Supplements or non-prescribed medications such as anabolic steroids. These variable and largely uncontrollable factors contribute to the well-known variation in semen composition among individuals. There is evidence that the results of one single ejaculate examination are enough to decide subsequent steps of an infertility investigation of the man. On the other hand, to define an exact baseline for an individual, it can be necessary to examine two or three ejaculates. While measurements made on the whole population of ejaculated spermatozoa cannot define the fertilizing capacity of the few that reach the site of fertilization, ejaculate analysis nevertheless provides essential information on the functional status of the reproductive organs of the individual. All aspects of ejaculate collection and examination must be assessed using properly standardized procedures if the results are to provide reliable – that is, valid and useful – information.
References:
WHO laboratory manual for the examination and processing of human semen, Sixth edition, 27 July 2021, Manual [L]
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A low semen volume, also known as hypospermia, can signify various underlying factors and may have implications for male reproductive health. Here's what it can signify:
→ Reduced Fertility: One of the primary concerns associated with low semen volume is reduced fertility. Semen carries and nourishes sperm, and a decreased volume may result in fewer sperm being available for fertilization, potentially leading to difficulties in achieving pregnancy.
→ Seminal Vesicle Issues: Semen volume is primarily derived from the seminal vesicles. Therefore, a low volume may indicate issues with these structures, such as absence or hypoplasia (underdevelopment), which can contribute to a reduced ejaculate volume.
→ Fluctuations in Volume: It's important to note that the volume of semen can naturally fluctuate from one ejaculation to another. Occasional low semen volume may not necessarily indicate a problem, as this can be influenced by factors like hydration, frequency of ejaculation, and overall health.
→ Medical Conditions: In some cases, low semen volume could be associated with underlying medical conditions or hormonal imbalances, such as low testosterone levels. It may also be linked to aging in some individuals.
→ Treatment Options: If low semen volume is a concern, individuals should consult a healthcare professional for a proper evaluation. Depending on the underlying cause, treatment options may include addressing any medical conditions, lifestyle changes, or assisted reproductive techniques for fertility issues.
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I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
Healthmatters is a highly-personalized health dashboard.
Instead of searching for your lab results in different places or tracking them down from different providers, Healthmatters houses, organizes, and interprets them all in one central location.
With a Healthmatters account, you can dive into the details of each biomarker and gain insights into the meaning behind your medical test data, anytime, anywhere.
For our professional users, Healthmatters provides intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history.
Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we work with many popular labs, we welcome reports from lots of other places too.
It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
If you’re on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.
There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."
Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.
For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.
We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.
Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.
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Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.
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Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.
Our goal has been to make your Healthmatters account as intuitive as possible.
We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
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3. Table View:For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.
Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.
Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.
Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.
Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
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Abstinence, Active sperm, Active sperm (10e6/ml), Agglutination Morphology, Amplitude of lateral hunting (ALH), Appearance, Average moving, Class A (fast), Class B (middle), Class C (slowly), Class D (slowly or not moving), Deformity rate, Density, Density of a+b, Liquefaction status, Liquefaction time, MAR-test IgA, MAR-test IgG, Morphology - leucocytes, Morphology - Round cells, Motility, Motility - immotil, Motility - not Progressive, Motility - Progressive, fast (A), Motility - Progressive, slow (B), Motility in fast rectilineal movement, Motility in rectilineal movement, Percent of a+b, pH, Semen pH, Seminal Fructose, Seminal neutral glucosidase, Seminal Zinc, Sperm concentration (density), Sperm count, Sperm density in fast rectilineal movement, Sperm density in rectilineal movement, Sperm morphology, Sperm motility, Sperm number in fast rectilineal movement, Sperm number in rectilineal movement, Total Motile Count, Total number, Velocity of active path (VAP), Velocity of curved line (VCL), Velocity of straight line (VSL), Viscosity, Volume, Volume of Semen / Ejaculate Volume
