Who should use Healthmatters?

Individuals who want to track and understand their health over time, health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.

What can I do with a Healthmatters account?

With a Healthmatters account, you can: Upload lab reports from any lab, View your data in interactive graphs, tables, and timelines, Track trends and monitor changes over time, Customize your reference ranges, Export and share your full lab history, Access your results anytime, from any device. Professionals can also analyze client data more efficiently and save time managing lab reports.

What test results do you interpret?

Healthmatters.io personal account provides in-depth research on 10000+ biomarkers, including information and suggestions for test panels such as, but not limited to: The GI Effects® Comprehensive Stool Profile, GI-MAP, The NutrEval FMV®, The ION Profile, Amino Acids Profile, Dried Urine Test for Comprehensive Hormones (DUTCH), Organic Acids Test, Organix Comprehensive Profile, Toxic Metals, Complete Blood Count (CBC), Metabolic panel, Thyroid panel, Lipid Panel, Urinalysis, And many, many more.

Do you only accept reports from specific labs listed here?

While we work with many popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

How do I get reports into my Healthmatters account?

There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our 'Data entry service.' Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values. For those who prefer assistance, we offer a 'Data entry service' to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.

What is the Data Entry Service, and why does it cost $15 per report?

Our Data Entry Service is for when you don't want to manually type in your lab results yourself. You simply upload your report (PDF, image, or screenshot), and our trained team enters the information into your Healthmatters account for you — accurately and neatly organized, ready to view in graphs, tables, and timelines. The $15 per report covers the time and care it takes for a real person to review your file, make sure each result is entered correctly, and double-check for accuracy. This ensures your health data is precise and easy to work with — without you having to spend the time doing it yourself. Prefer to do it yourself? You can always use our free self-entry tool to add results manually — it just takes a bit more time and attention.

Does a personal account come with a data entry service?

For users on the Advanced Plan, the first 5 reports are included free of charge, and each additional report incurs a $15 fee. Unlimited Plan holders enjoy the entry of 10 reports at no charge. Subsequent reports are subject to a $15 fee per report. Additionally, users on the Advanced Plan can upgrade to the Unlimited Plan from their account settings.

How much does a professional account cost?

All professional accounts allow you to import and onboard an unlimited number of clients and their lab results. The distinction between professional plans lies solely in the data entry service. The Pro Monthly Plus plan is priced at $75 per month and includes a data entry service for five reports each month. Additional reports can be self-entered at no extra cost or, if preferred, you can use our data entry service for an additional fee of $15 per report. The Pro Monthly plan is priced at $45 per month and does not include a data entry service. Self-entry is free for an unlimited number of reports, and you can opt for the data entry service at a fee of $15 per report. You also have the option to upgrade to higher monthly or to annual plans, which come with substantial discounts. All upgrades can be done directly from your account.

How do I terminate my account?

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Can I download my information from my account?

Yes, you can download your information anytime. We offer two easy ways to export your lab data: 1. Download a CSV file: Go to Account Settings and scroll to the bottom of the page. There, you'll find a link to download all your labs as a CSV file. 2. Download an Excel file: To export your data in Excel format, go to either the Graph or Table view and click “Export Excel File.”

Can I print my report?

Yes, you can print your report. To do so, navigate to 'All tests' and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

Can I secure my account with Two-Factor Authentication (2FA)?

Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the 'Profile and Security' section of your account, where you will find instructions for activating 2FA.

Can I use a custom range for biomarkers?

Yes, you can. When entering values for the biomarker, you will see an 'Edit Range' button. Click this button, and you'll have the option to enter a custom range.

What’s the difference between personal and professional accounts?

A personal account is all about keeping your own lab test results in check. It's just for you and your personal use. The professional account is designed for health professionals who wish to track and organize their clients' laboratory results.

Where can I learn more about professional accounts?

To learn more about Healthmatters Pro, please refer to the professional page.

Can I share my results in the HealthMatters dashboard with my doctor?

Yes, you can! Simply go to the 'Invite Doctor' section, enter your doctor’s email address, and send the invitation. Your doctor will receive an email with secure access to view your results. You can revoke this access at any time. All shared information is securely encrypted and protected for your privacy.

Can I export my information to an Excel file?

Yes, you can! Go to the Graph view or Spreadsheet view. In the top-right corner, click 'Export to Excel,' and the file will be downloaded to your device.

Tryptophan

Urine

Optimal Result: 30 - 100 µmol/g Crea.

Neurotransmitter XL getTested

Tryptophan is an essential amino acid that serves as the biochemical starting point for several key pathways in the body. It is the primary precursor for serotonin—the neurotransmitter responsible for emotional balance, sleep regulation, and relaxation—and, by extension, for melatonin, which governs circadian rhythm and sleep quality. Beyond neurotransmission, tryptophan also plays a vital role in immune modulation, energy production, and cellular repair, making it one of the most metabolically significant amino acids tested in the Neurotransmitter XL panel.

Because the body cannot synthesize tryptophan, it must be obtained from dietary sources such as turkey, eggs, salmon, tofu, legumes, nuts, and seeds. Once absorbed, tryptophan follows multiple metabolic routes, including:

Serotonin pathway – for neurotransmitter and melatonin synthesis.
Kynurenine pathway – for immune regulation, production of NAD+ (nicotinamide adenine dinucleotide), and energy metabolism.
Protein synthesis – incorporation into structural and enzymatic proteins.

The balance between serotonin production and kynurenine metabolism provides deep insight into how the body manages stress, inflammation, and mood.

Why It Matters on the Neurotransmitter XL Panel

On the Neurotransmitter XL panel, tryptophan is measured alongside serotonin, kynurenine, quinolinic acid, and NAD+ to evaluate how efficiently the body converts this amino acid into neurotransmitters or energy-related cofactors.

This is particularly important because tryptophan metabolism shifts under stress, inflammation, or immune activation. When chronic stress or inflammatory cytokines trigger the enzyme indoleamine 2,3-dioxygenase (IDO), tryptophan is diverted away from serotonin synthesis toward the kynurenine pathway. This can result in:

Reduced serotonin and melatonin production, leading to mood changes, fatigue, and sleep disturbances.
Accumulation of neurotoxic metabolites such as quinolinic acid, which can impair mitochondrial function.
Reduced NAD+ formation, decreasing ATP output and energy availability.

By examining tryptophan in conjunction with its downstream metabolites, the panel helps identify whether the imbalance arises from nutritional deficiencies, inflammatory stress, or mitochondrial dysfunction.

Physiology and Metabolic Pathways

1. Serotonin and Melatonin Synthesis

Tryptophan → 5-HTP → Serotonin (5-HT) → Melatonin

Tryptophan hydroxylase (TPH) converts tryptophan to 5-HTP (requires BH4, iron, and oxygen).
Aromatic L-amino acid decarboxylase (AADC) converts 5-HTP to serotonin (requires vitamin B6).
In the pineal gland, serotonin is acetylated and methylated to form melatonin, a process dependent on SAM (S-adenosylmethionine).

Deficiencies in vitamin B6, BH4, folate, B12, magnesium, or SAM can slow this pathway, resulting in low serotonin and melatonin levels.

2. The Kynurenine Pathway

Tryptophan → Kynurenine → Quinolinic Acid → NAD+

When stress or immune activation induces IDO or tryptophan 2,3-dioxygenase (TDO), more tryptophan is converted into kynurenine and its downstream metabolites.
This pathway has dual roles: it helps regulate immune responses, but excessive activation can deplete serotonin and produce oxidative or neurotoxic byproducts.

Markers like kynurenine, quinolinic acid, NAD+, and neopterin on the panel indicate how this pathway is functioning.

Elevated kynurenine – reflects inflammatory activation or stress load.
High quinolinic acid – suggests oxidative stress and potential mitochondrial toxicity.
Low NAD+ – points to impaired conversion or nutrient depletion (e.g., low niacin).

Factors That Influence Tryptophan Levels and Metabolism

1. Dietary Intake and Protein Balance

Tryptophan competes with other large neutral amino acids (LNAAs) for transport across the blood–brain barrier.

High-protein meals can limit its uptake into the brain.
Carbohydrate intake can improve tryptophan availability by promoting insulin-mediated uptake of competing amino acids.

Low dietary tryptophan or restricted diets (e.g., vegan or low-protein) can therefore limit serotonin synthesis.

2. Vitamin and Cofactor Status

Efficient tryptophan metabolism requires:

Vitamin B6 for decarboxylation into serotonin.
Folate, B12, and SAM for methylation processes.
Vitamin C and iron for hydroxylation steps.
Niacin (B3) for NAD+ generation.
Deficiencies in these cofactors can result in incomplete conversion and accumulation of intermediary metabolites.

3. Stress, Cortisol, and Immune Activation

Chronic stress elevates cortisol and inflammatory cytokines (e.g., interferon-γ), activating the IDO enzyme that diverts tryptophan from serotonin to kynurenine.
This can cause:

Decreased serotonin and melatonin (affecting mood and sleep)
Elevated quinolinic acid and kynurenine (increasing oxidative and nitrosative stress)
Reduced NAD+ synthesis (impairing mitochondrial energy production)

This “tryptophan steal” phenomenon explains why prolonged stress often leads to low mood, fatigue, and burnout symptoms.

4. Gut Health and Microbiome

The gut microbiome influences tryptophan metabolism directly. Certain bacteria metabolize tryptophan into indoles, which regulate immune and intestinal barrier function.
Chronic gut inflammation or dysbiosis can therefore lower tryptophan availability or skew its metabolic pathways.

5. Mitochondrial Function and Energy Status

Mitochondrial health influences NAD+ turnover and the efficiency of tryptophan conversion.
Low ATP production, oxidative stress, or environmental toxin exposure (e.g., phthalates) can inhibit key enzymes like quinolinic acid phosphoribosyltransferase (QPRT), leading to NAD+ deficiency even when tryptophan intake is adequate.

Interpretation Context on Neurotransmitter XL

Related Marker	Interpretation Insight
Serotonin	Low serotonin with low tryptophan suggests precursor deficiency; low serotonin with normal tryptophan suggests pathway blockage or cofactor deficiency.
Kynurenine	Elevated levels indicate stress- or immune-driven diversion of tryptophan metabolism.
Quinolinic Acid	High levels point to oxidative stress and possible mitochondrial impairment.
NAD+ and Niacin Markers	Low levels reflect impaired energy metabolism and incomplete conversion of quinolinic acid to NAD+.
Neopterin	Elevated neopterin suggests immune activation (via interferon-γ) leading to IDO stimulation.
SAM / SAH Ratio	Low ratio indicates reduced methylation capacity affecting melatonin synthesis and overall neurotransmitter balance.

Low Tryptophan – What It Can Indicate

Inadequate dietary intake or absorption issues
Chronic inflammation or stress diverting tryptophan to the kynurenine pathway
Cofactor deficiencies (vitamin B6, folate, B12, iron, or BH4) limiting serotonin synthesis
Malabsorption or gut dysbiosis reducing precursor availability
Mitochondrial dysfunction lowering NAD+ conversion efficiency

Symptoms may include low mood, anxiety, fatigue, poor sleep, cravings for carbohydrates, and digestive issues.

Elevated Tryptophan – What It Can Indicate

Less common, but may occur with:

Reduced conversion efficiency (enzyme or cofactor deficiencies)
Blocked downstream metabolism (e.g., IDO or TDO inactivity)
Supplementation with tryptophan or 5-HTP
Persistent elevation without proportional increases in serotonin or kynurenine may indicate metabolic stagnation or impaired enzyme activity.

Long-Term Implications

Imbalances in tryptophan metabolism can have wide-ranging effects:

Mood and sleep disturbances due to low serotonin and melatonin
Neuroinflammation and fatigue from excess quinolinic acid
Impaired cellular energy due to low NAD+ and mitochondrial strain
Immune dysregulation through disrupted kynurenine signaling

Addressing the root cause—whether nutritional, inflammatory, or mitochondrial—can help restore balanced tryptophan utilization.

Supportive Strategies to Discuss with Your Clinician

Ensure adequate dietary protein with balanced amino acid intake.
Support serotonin synthesis with vitamin B6, folate, B12, magnesium, iron, and BH4 cofactors.
Mitigate chronic stress through mindfulness, restorative sleep, and moderate exercise.
Support mitochondrial health with niacin (B3), NAD+ precursors, CoQ10, and antioxidants.
Promote gut health via probiotics, prebiotics, and anti-inflammatory nutrition.
Consider targeted supplementation with tryptophan or 5-HTP only under clinical supervision, especially if taking SSRIs or other serotonergic agents.

Key Takeaway

Tryptophan sits at the crossroads of neurotransmitter synthesis, immune regulation, and mitochondrial energy metabolism. Low levels or pathway imbalances can reveal why an individual feels fatigued, anxious, or unable to recover from stress. On the Neurotransmitter XL panel, tryptophan results—interpreted alongside serotonin, kynurenine, NAD+, and neopterin—offer a powerful lens into how the body converts nutrients into emotional and physical vitality.

All Your Lab Results.
One Simple Dashboard.

Import, Track, and Share Your Lab Results Easily

Import, Track, and Share Your Lab Results

Import lab results from multiple providers, track changes over time, customize your reference ranges, and get clear explanations for each result. Everything is stored securely, exportable in one organized file, and shareable with your doctor—or anyone you choose.

Cancel or upgrade anytime

What does it mean if your Tryptophan result is too low?

A decreased tryptophan level on the Neurotransmitter XL panel suggests that the body may not be receiving, absorbing, or utilizing this essential amino acid efficiently. Because tryptophan is the precursor to serotonin, melatonin, and nicotinamide adenine dinucleotide (NAD+), low levels can disrupt multiple systems—impacting mood, sleep, stress resilience, energy production, and immune regulation. When tryptophan becomes depleted, serotonin synthesis declines, sleep quality worsens, and the body may divert remaining stores toward the kynurenine pathway, especially under chronic stress or immune activation.

Key Mechanisms Behind Low Tryptophan

1. Dietary Deficiency or Malabsorption

Tryptophan is an essential amino acid—the body cannot produce it internally. Insufficient intake of protein-rich foods (such as poultry, eggs, fish, or legumes) can directly lower circulating levels. Additionally, malabsorption syndromes, gut inflammation, or microbiome imbalances can reduce intestinal absorption, even when dietary intake is adequate.

2. Chronic Stress and Cortisol Activation

Prolonged stress increases cortisol and activates indoleamine 2,3-dioxygenase (IDO)—an enzyme that diverts tryptophan away from serotonin and toward the kynurenine pathway. This “tryptophan steal” reduces serotonin synthesis, promotes neurotoxic byproducts like quinolinic acid, and depletes mitochondrial NAD+, which is essential for energy metabolism. Over time, this shift contributes to fatigue, low mood, and burnout.

3. Inflammation and Immune Activation

During immune or inflammatory responses, interferon-γ and other cytokines further stimulate IDO, accelerating tryptophan depletion. Elevated neopterin levels on the panel often accompany this pattern, indicating active immune-mediated diversion of tryptophan metabolism. This mechanism is common in chronic inflammatory or autoimmune conditions.

4. Vitamin and Cofactor Deficiencies

Efficient conversion of tryptophan into serotonin and NAD+ requires several cofactors:

Vitamin B6 (for serotonin synthesis)
Folate, B12, and BH4 (for methylation and hydroxylation)
Niacin (B3) (for NAD+ synthesis)
Iron and magnesium (for enzymatic reactions)
Deficiencies in these nutrients can hinder tryptophan’s normal metabolic flow, resulting in accumulation of incomplete intermediates or redirection into stress pathways.

5. Gut Dysbiosis and Microbiome Disturbances

Up to 90% of serotonin is produced in the gut. Dysbiosis, intestinal inflammation, or “leaky gut” can impair local tryptophan metabolism and reduce precursor availability for serotonin synthesis. Certain beneficial gut bacteria—like Bifidobacterium and Lactobacillus—help convert tryptophan into serotonin and other indole derivatives that maintain intestinal and nervous system balance.

6. Overtraining, Sleep Deprivation, or Excessive Stimulant Use

Intense physical training, chronic sleep loss, caffeine, and stimulant use increase catecholamine turnover and stress hormone production, consuming tryptophan reserves faster than they can be replenished.

Common Symptoms of Low Tryptophan

Because tryptophan influences both neurotransmitter and mitochondrial systems, low levels can manifest as:

Low mood, depression, or emotional flatness
Anxiety, irritability, or poor stress tolerance
Fatigue, low motivation, or burnout
Sleep disturbances (especially early waking or insomnia)
Increased pain sensitivity
Digestive discomfort or altered bowel patterns
Carbohydrate cravings (a compensatory mechanism to increase serotonin)

Interpretation Context on Neurotransmitter XL

Related Marker	Interpretation Insight
Serotonin	Low serotonin alongside low tryptophan indicates substrate deficiency; low serotonin with normal tryptophan suggests cofactor or enzyme block.
Kynurenine / Quinolinic Acid	Elevated levels with low tryptophan suggest immune or stress-induced diversion.
NAD+ / Niacin Markers	Low values reflect impaired energy production due to reduced tryptophan conversion.
Neopterin	High values indicate immune activation driving IDO activity.
BH4 and B6 Markers (Cystathionine, Methylmalonic Acid)	Elevated markers suggest cofactor insufficiency limiting serotonin synthesis.

This integrated analysis helps determine whether low tryptophan arises from nutrient deficiency, inflammation, immune activity, or stress-related metabolic shifts.

Clinical and Metabolic Implications

Persistent tryptophan depletion can lead to:

Serotonin and melatonin deficiency, affecting mood, sleep, and circadian rhythm.
Reduced NAD+ production, impairing mitochondrial energy metabolism.
Neuroinflammation, driven by excess kynurenine and quinolinic acid.
Emotional instability, fatigue, and burnout, linked to low neurotransmitter synthesis.

Early recognition and intervention are key to preventing downstream neurochemical and metabolic imbalances.

Supportive Strategies to Discuss with Your Clinician

Optimize protein intake: Include tryptophan-rich foods (turkey, salmon, eggs, oats, pumpkin seeds).
Replete cofactors: Ensure adequate B6, B12, folate, niacin (B3), magnesium, iron, and zinc.
Mitigate chronic stress: Prioritize relaxation, restorative sleep, and moderate exercise.
Support gut health: Address inflammation and encourage beneficial microbiota through probiotics and fiber-rich foods.
Reduce inflammatory load: Manage chronic infections, metabolic stress, and environmental toxin exposure.
Monitor supplementation carefully: L-tryptophan or 5-HTP may support serotonin synthesis under medical supervision, especially if not using serotonergic medications.

Key Takeaway

Low tryptophan levels signify a disruption in the body’s ability to generate serotonin, melatonin, and NAD+—core molecules for mood, sleep, and energy regulation. Whether due to stress, inflammation, nutrient deficiency, or poor gut function, this imbalance can contribute to fatigue, anxiety, and emotional instability. Interpreting tryptophan alongside serotonin, kynurenine, NAD+, neopterin, and B-vitamin markers on the Neurotransmitter XL panel provides a detailed picture of underlying biochemical imbalances.

Laboratories

Bring All Your Lab Results Together — In One Place

We accept reports from any lab, so you can easily collect and organize all your health information in one secure spot.

Pricing Table

Gather Your Lab History — and Finally Make Sense of It

Finally, Your Lab Results Organized and Clear

Choose the plan that fits you — and turn scattered lab reports into clear insights you can finally use.

Pick a plan that fits you — and turn scattered lab reports into clarity.

Personal plans

Professional plan

$79/ year

Advanced Plan

Access your lab reports, explanations, and tracking tools.

Import lab results from any provider
Track all results with visual tools
Customize your reference ranges
Export your full lab history anytime
Share results securely with anyone
Receive 5 reports entered for you
Cancel or upgrade anytime

$250/ once

Unlimited Account

Pay once, access everything—no monthly fees, no limits.

Import lab results from any provider
Track all results with visual tools
Customize your reference ranges
Export your full lab history anytime
Share results securely with anyone
Receive 10 reports entered for you
No subscriptions. No extra fees.

Professional plan

$45/ month

Pro Monthly

Designed for professionals managing their clients' lab reports

Import lab results from any provider
Track lab results for multiple clients
Customize reference ranges per client
Export lab histories and reports
Share results and reports with clients
Invite clients to their accounts
Begin with first report entered by us
Cancel or upgrade anytime

About membership

What's included in a Healthmatters membership

Import Lab Results from Any Source

Easily upload lab results from any provider, whether it's a hospital, independent lab, or home testing service. We support PDFs, scanned documents, and JPEGs from patient portals. No need to log in to multiple platforms — everything is centralized in one secure space.

Easily upload lab results from any provider — we support PDFs, scans, and images. Keep all your reports organized in one secure place.

See Your Health Timeline

Every lab result is automatically organized on a chronological timeline, giving you a complete picture of your health journey. Whether you're tracking a condition, managing treatments, or staying proactive, the timeline helps you and your doctor understand how things progress over time.

Every lab result is automatically organized on a chronological timeline, giving you a complete picture of your health journey.

Understand What Your Results Mean

Whether it's a blood test, GI panel, urinalysis, or something else, lab reports measure numerous biomarkers that reveal what's happening inside your body. Our extensive database covers over 10,000 biomarkers, providing clear, simple explanations of what each result means and how you can take action—no matter your membership level. Say goodbye to confusion and get the insights you need to better understand your health.

Our database covers over 10,000 biomarkers with clear, simple explanations—so you can finally understand your results and what to do next.

Enter Your Lab Reports Yourself — Always Free Enter Your Lab Reports — Always Free

If you'd like to handle inputting your health data into your account, you can do so with our easy-to-use data entry forms. Our user-friendly form is designed to guide you through the quick and easy submission process, making it simple to keep track of your health metrics. This is available to both Advanced plan and Unlimited plan members.

Our user-friendly form guides you through a quick, simple submission process, making it easy to enter your health metrics.

Add your results anytime with our easy entry form. It's quick, guided, and helps you stay organized — free for all members.

Visualize Your Results

View your lab data through easy-to-read graphs and tables. Quickly spot patterns, track changes, and compare results across different dates — all without digging through multiple reports. You can also select and compare graphs of specific biomarkers side-by-side to better understand how they relate and change over time.

See your lab reports in clear graphs and tables. Spot patterns, track changes, and compare results over time — all in one place.

Export Your Complete Lab History in a Single File Export Your Complete Lab History

After collecting lab results from different providers, you can download your entire history combined into a single file. Choose from PDF, Excel, or CSV formats to easily review, share, or get a second opinion—no more juggling multiple reports.

After collecting lab results from different providers, you can download your entire history combined into a single file.

Comprehensive Data Entry Service for Your Reports Data Entry Service for Your Reports

Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest. Advanced plan members receive five reports entered for free, then $15 per report after that. Unlimited plan members receive ten report entries for free, then $15 per report after that.

Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest.

Securely Share With Anyone You Trust

Whether you're working with a doctor, nutritionist, caregiver, or wellness coach, you can securely share your complete lab history by sending an invite link to anyone you trust. You have full control over who sees your information and for how long, ensuring your privacy and peace of mind at every step.

Share your full lab history with your doctor, nutritionist, or coach using a secure invite link.

Discover

Let Your Lab Results Tell the Full Story

Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.

Bring all your results together to compare, track progress, export your history, and share securely.

I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.

Anthony

Unlimited Plan Member since 2021

What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!

Karin

Advanced Plan Member since 2020

As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!

Paul

Healthmatters Pro Member since 2024

Frequently asked questions

Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.

Individuals who want to track and understand their health over time.
Health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.

With a Healthmatters account, you can:

Upload lab reports from any lab
View your data in interactive graphs, tables, and timelines
Track trends and monitor changes over time
Customize your reference ranges
Export and share your full lab history
Access your results anytime, from any device

Professionals can also analyze client data more efficiently and save time managing lab reports.

Healthmatters.io personal account provides in-depth research on 10000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

The GI Effects® Comprehensive Stool Profile,
GI-MAP,
The NutrEval FMV®,
The ION Profile,
Amino Acids Profile,
Dried Urine Test for Comprehensive Hormones (DUTCH),
Organic Acids Test,
Organix Comprehensive Profile,
Toxic Metals,
Complete Blood Count (CBC),
Metabolic panel,
Thyroid panel,
Lipid Panel,
Urinalysis,
And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

The Advanced Plan ($79/year) is perfect for individuals who want ongoing access to their health data. It includes unlimited self-entry of lab reports, visual tracking, custom ranges, result explanations, full account exports, and secure sharing — all with a simple yearly subscription. The plan also includes free data entry of up to 5 reports by our data entry team. You can cancel anytime and restart your plan whenever you're ready — your data will still be there waiting for you. You can also upgrade to the Unlimited Plan at any time, with the cost prorated based on what you've already paid.

The Unlimited Plan ($250 one-time) is also designed for individuals but offers lifetime access with no ongoing subscription. You'll get all the same features as the Advanced Plan, plus free data entry of up to 10 reports by our data entry team, making it a great choice if you prefer a one-time payment and long-term use without yearly fees.

In short:

Advanced Plan → Best for those who want to try the service for less (cancel/restart anytime, upgrade to Unlimited anytime).
Unlimited Plan → Best for long-term users who prefer to pay once and keep access forever.

Our goal has been to make your Healthmatters account as intuitive as possible.

We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

Tryptophan

Why It Matters on the Neurotransmitter XL Panel

Physiology and Metabolic Pathways

1. Serotonin and Melatonin Synthesis

2. The Kynurenine Pathway

Factors That Influence Tryptophan Levels and Metabolism

1. Dietary Intake and Protein Balance

2. Vitamin and Cofactor Status

3. Stress, Cortisol, and Immune Activation

4. Gut Health and Microbiome

5. Mitochondrial Function and Energy Status

Interpretation Context on Neurotransmitter XL

Low Tryptophan – What It Can Indicate

Elevated Tryptophan – What It Can Indicate

Long-Term Implications

Supportive Strategies to Discuss with Your Clinician

Key Takeaway

All Your Lab Results. One Simple Dashboard.

Import, Track, and Share Your Lab Results Easily

Import, Track, and Share Your Lab Results

What does it mean if your Tryptophan result is too low?

Key Mechanisms Behind Low Tryptophan

1. Dietary Deficiency or Malabsorption

2. Chronic Stress and Cortisol Activation

3. Inflammation and Immune Activation

4. Vitamin and Cofactor Deficiencies

5. Gut Dysbiosis and Microbiome Disturbances

6. Overtraining, Sleep Deprivation, or Excessive Stimulant Use

Common Symptoms of Low Tryptophan

Interpretation Context on Neurotransmitter XL

Clinical and Metabolic Implications

Supportive Strategies to Discuss with Your Clinician

Key Takeaway

Bring All Your Lab Results Together — In One Place

Gather Your Lab History — and Finally Make Sense of It

Finally, Your Lab Results Organized and Clear

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Import Lab Results from Any Source

See Your Health Timeline

Understand What Your Results Mean

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Export Your Complete Lab History in a Single File Export Your Complete Lab History

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Securely Share With Anyone You Trust

Let Your Lab Results Tell the Full Story

Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.

Bring all your results together to compare, track progress, export your history, and share securely.

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