Total Prostate Specific Antigen (TPSA)

Optimal Result: 0 - 1.4 ug/L.

Total Prostate Specific Antigen (TPSA) is a serine protease produced by prostate cells, primarily used as a biomarker for the screening and monitoring of prostate cancer. While elevated TPSA levels can indicate the presence of prostate cancer, they can also arise from benign conditions such as benign prostatic hyperplasia (BPH) and prostatitis. The TPSA test measures the total amount of PSA in the blood, which includes both free and protein-bound forms. Although TPSA is a valuable tool in early detection and management of prostate cancer, its specificity is limited, as elevated levels can occur in non-cancerous conditions. Therefore, healthcare providers often use additional tests, such as the free-to-total PSA ratio, to improve diagnostic accuracy and differentiate between benign and malignant prostate conditions.

What does it mean if your Total Prostate Specific Antigen (TPSA) result is too high?

Elevated Total Prostate Specific Antigen (TPSA)

An elevated TPSA level can signify several conditions, including:

→ Prostate cancer: TPSA levels tend to be higher in men with prostate cancer, especially if the cancer is more aggressive.

→ Benign prostatic hyperplasia (BPH): An enlarged prostate due to BPH can cause elevated TPSA levels.

→ Prostatitis: Inflammation of the prostate, known as prostatitis, can also lead to increased TPSA.

However, it's important to note that a high TPSA level does not necessarily mean prostate cancer is present. Other factors, such as age and prostate size, can influence TPSA levels.

Treatment Options

The treatment options for elevated TPSA depend on the underlying cause and the individual's overall health and preferences. Some common treatment approaches include:

  1. Active surveillance: For men with low-risk prostate cancer or elevated TPSA due to BPH, active surveillance may be recommended. This involves regular monitoring of TPSA levels and other tests to detect any changes that may require treatment.
  2. Medications: Medications like 5-alpha reductase inhibitors (5-ARIs) can help reduce TPSA levels in men with BPH by shrinking the prostate.
  3. Radiation therapy: For men with prostate cancer, radiation therapy may be used to treat the cancer and potentially lower TPSA levels.
  4. Surgery: Surgical options, such as radical prostatectomy, may be considered for men with localized prostate cancer. This involves removing the entire prostate gland and can lead to a reduction in TPSA levels.
  5. Antibiotics: If prostatitis is the cause of elevated TPSA, antibiotics may be prescribed to treat the infection and potentially lower TPSA levels.

It's crucial to consult with a healthcare professional to determine the appropriate treatment plan based on the individual's specific condition, TPSA levels, and overall health status.

Frequently asked questions

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It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

If you’re on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.

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Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.

For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.

We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.

Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.

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Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Our goal has been to make your Healthmatters account as intuitive as possible.

We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

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For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.

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Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.

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