b-Tetrahydrocortisone (b-THE) is an adrenal steroid and a cortisol metabolite. Tetrahydrocortison (THE) is a down-stream metabolite of cortisol and cortisone. Excess cortisol will result in high levels of urinary b-Tetrahydrocortisone (b-THE). Cortisone is a pregnane steroid hormone closely related to cortisol. It is one of the main hormones released by the adrenal gland in response to stress. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone. Cortisone, a glucocorticoid, and epinephrine (adrenaline) are the main substances released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response.
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