Sources:
Niobiumis sometimes found in jewelry, and is used with other alloys, like titanium, to make surgical implants and dental applications. It is also a component of superconducting magnets and nuclear reactor cores.
Physiologic effects:
Niobium is poorly absorbed from the GI tract.
Clinical significance:
It is a moderate eye and skin irritant. Due to poor GI absorption, it has a low order of toxicity. Lethargy and respiratory depression have only been seen with parenteral administration.
References:
Hayes AW. Principles and methods of toxicology. Crc Press; 2007.
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