Mycoplasma refers to a genus of bacteria that lack a cell wall, which makes them immune to common antibiotics such as penicillin. Mycoplasma pneumoniae, Mycoplasma arthritidis and ureaplasma are common human pathogens. The lack of rigid cell wall allows mycoplasmas to have direct and intimate contact with the cytoplasmic membrane of the host cell leading to cell fusion and delivery of lipid-associated membrane proteins (LAMPS). LAMPS are highly antigenic and hence are major mechanisms of Mycoplasma-induced autoimmune reactivity.
Mycoplasmas
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