Two types of antibodies are detected in the Western blot test.
IgM antibodies reflect a relatively recent infection. IgG antibodies in contrast are a sign of an older infection.
IgM antibodies usually disappear after eight weeks post-exposure.
IgG remains in the serum for a very long time.
In the Western blot test there are three bands for IgM and 10 bands for IgG.
Here is the important part:
- You need to have 2 out of 3 for the positive IgM result
- Or you need to have 5 out of 10 for the positive IgG result.
This marker is called Lyme Disease AB (IGM), Blot and is an aggregate marker for the three IgM results. So if this marker is positive you have at least 2 out of 3 of the IgM markers positive.
Every lab result you’ve ever had, charted and explained.
Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.
Start with my report →All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.