Interferon gamma (IFN-γ) is a helper T-cell 1 (Th1)-derived cytokine and plays a critical role for both innate and adaptive immunity against viral and intracellular bacterial infections and tumor control.
Interferon gamma (IFN-γ) is one of the key proinflammatory cytokine central to many biological processes. The changes in serum IFN-γ concentrations were found in many diseases such as psoriasis, systemic lupus erythematosus and lichen planus. In some of these diseases, serum IFN-γ concentration correlated with activity and intensity of the disease, and may be used as a prognostic factor.
References:
Kurtovic, Nermina Ovcina, and Emina Kasumagic Halilovic. “Serum Concentrations of Interferon Gamma (IFN-γ) in Patients with Psoriasis: Correlation with Clinical Type and Severity of the Disease.” Medical archives (Sarajevo, Bosnia and Herzegovina) vol. 72,6 (2018): 410-413. doi:10.5455/medarh.2018.72.410-413
Interferon Gamma, Serum
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