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Histoplasma Antigen, Serum

Optimal result: 0 – 0.5 ng/mL
By Healthmatters Editorial Team
Peer-reviewed sources

Abnormal results may mean you have an active histoplasmosis infection or have had an infection in the past.

During the early stage of an illness, few antibodies may be detected. Antibody production increases during the course of an infection. For this reason, this test may be repeated several weeks after the first test.

People who have been exposed to H capsulatum in the past may have antibodies to it, often at low levels. But they may not have shown signs of illness.

Histoplasma complement fixation is a blood test that checks for infection from a fungus called Histoplasma capsulatum (H capsulatum), which causes the disease histoplasmosis.

Histoplasma antigen detection by ELISA is a widely performed test for the diagnosis of histoplasmosis, especially those with suspected acute pulmonary or disseminated histoplasmosis. Histoplasmosis is an infection caused by a fungus called Histoplasma. The fungus lives in the environment, particularly in soil that contains large amounts of bird or bat droppings.

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