Hemoglobin (Hgb) S. This type of hemoglobin is found in sickle cell disease. Sickle cell disease is an inherited disorder that causes the body to make stiff, sickle-shaped red blood cells. Healthy red blood cells are flexible so they can move easily through blood vessels. Sickle cells can get stuck in the blood vessels, causing severe and chronic pain, infections, and other complications.
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