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BiomeFx Microbiome Labs

Glutathione production

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Optimal Result: 15.809 - 34.812 Healthy Relative Abundance IQR (%).

Glutathione Production on a BiomeFx Panel

Glutathione is a powerful antioxidant produced in the body, playing a critical role in protecting cells from oxidative stress and maintaining overall cellular health. On a BiomeFx panel, the marker for glutathione production indicates the capacity of the gut microbiota to contribute to the synthesis of this vital molecule. Adequate glutathione levels are essential for detoxification processes, immune function, and the neutralization of free radicals. Low levels of glutathione production can be associated with increased susceptibility to chronic diseases, inflammation, and compromised immune response. Factors influencing glutathione production include diet, lifestyle, gut health, and genetic predispositions. Monitoring and supporting glutathione production through nutritional interventions, such as increasing intake of sulfur-rich foods (e.g., garlic, onions, cruciferous vegetables), antioxidants, and specific supplements, can enhance the body’s antioxidant defenses and promote overall well-being.

What does it mean if your Glutathione production result is too high?

Increased levels of Glutathione production on a BiomeFx panel can provide insights into various aspects of gut health and systemic health. Here’s a comprehensive overview:

What Increased Levels of Glutathione Production Signify

Glutathione is a powerful antioxidant that helps protect cells from oxidative stress and detoxifies harmful substances. Increased levels of Glutathione production on a BiomeFx panel may indicate:

  1. Enhanced Detoxification: The body might be responding to higher levels of toxins or oxidative stress.
  2. Gut Microbiome Health: Certain gut bacteria can produce glutathione, indicating a specific composition of the gut microbiome.
  3. Inflammatory Response: The body might be combating inflammation or infection.

Conditions Associated with Increased Levels

  1. Chronic Inflammation: Conditions like inflammatory bowel disease (IBD) or other chronic inflammatory conditions.
  2. Oxidative Stress: Conditions that involve high oxidative stress, such as chronic diseases and environmental toxin exposure.
  3. Liver Disease: The liver produces and uses glutathione extensively for detoxification.
  4. Cancer: Increased production might be a response to cancerous cells.
  5. Autoimmune Diseases: These conditions often involve oxidative stress and inflammation.

Possible Reasons for Increased Levels

  1. Diet: High intake of foods rich in antioxidants and precursors to glutathione (e.g., sulfur-containing foods like garlic, onions, and cruciferous vegetables).
  2. Supplementation: Direct supplementation of glutathione or its precursors like N-acetylcysteine (NAC).
  3. Environmental Toxins: Exposure to high levels of environmental toxins requiring detoxification.
  4. Microbial Composition: Certain beneficial bacteria in the gut can produce glutathione.
  5. Genetic Factors: Genetic predispositions that increase glutathione production.

Potential Treatment Considerations

  1. Address Underlying Conditions: Treat any underlying chronic inflammation, infection, or disease contributing to oxidative stress.
  2. Dietary Adjustments: Ensure a balanced diet that supports gut health and reduces oxidative stress.
  3. Probiotics and Prebiotics: Support a healthy gut microbiome to promote balanced glutathione production.
  4. Reduce Toxin Exposure: Minimize exposure to environmental toxins.
  5. Supplementation: Consider appropriate supplementation under medical guidance, such as NAC or glutathione precursors.
  6. Antioxidant Support: Ensure adequate intake of other antioxidants to balance oxidative stress.

Correlated Biomarkers

  1. Oxidative Stress Markers: Such as lipid peroxides or malondialdehyde (MDA).
  2. Inflammatory Markers: C-reactive protein (CRP), interleukin-6 (IL-6).
  3. Liver Function Tests: ALT, AST, and bilirubin levels.
  4. Microbial Metabolites: Specific short-chain fatty acids (SCFAs) and other metabolites indicating gut health.

Nutrient Associations

  1. Sulfur-Containing Amino Acids: Methionine, cysteine.
  2. Vitamins and Minerals: Vitamins C and E, selenium, magnesium.
  3. Polyphenols: Found in fruits, vegetables, and certain beverages like tea and coffee.

Specific Considerations

  • Males vs. Females: Hormonal differences can affect oxidative stress and glutathione metabolism. For example, estrogen has antioxidant properties which might influence glutathione levels.
  • Young vs. Old: Aging is associated with decreased natural production of glutathione. Older individuals might have higher oxidative stress and thus increased production as a compensatory mechanism.

By evaluating these factors in conjunction, a more comprehensive understanding of a patient’s glutathione levels can be achieved, aiding in tailored treatment and management strategies.

Frequently asked questions

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With a Healthmatters account, you can dive into the details of each biomarker and gain insights into the meaning behind your medical test data, anytime, anywhere.

For our professional users, Healthmatters provides intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history.

Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

  • The GI Effects® Comprehensive Stool Profile,
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  • Amino Acids Profile,
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If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

While we work with many popular labs, we welcome reports from lots of other places too.

It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

If you’re on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.

There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."

Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.

For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.

We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.

Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.

Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.

For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.

Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.

Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.

The Unlimited plan is a one-time purchase for $250, and it covers your account for a lifetime with no additional payments.

For the Complete plan, the cost is $15 per month. You have the flexibility to cancel it anytime through your account settings, ensuring no further payments. To avoid charges, remember to cancel at least a day before the renewal date. Once canceled, the subscription remains active until the end of the current billing cycle.

Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.

You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Our goal has been to make your Healthmatters account as intuitive as possible.

We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.

Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.

Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.

A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.

The professional account is designed for health professionals who wish to track and organize their clients' laboratory results.

To learn more about Healthmatters Pro, please refer to the professional page.

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