Factor VII Activity

Optimal result: 51 – 186 %

By Healthmatters Editorial Team

Peer-reviewed sources

- Congenital factor VII deficiency is rare and is inherited as one of several autosomal recessive mutations.

- Acquired factor VII deficiency is caused by liver disease, vitamin K deficiency or the use of Coumadin (warfarin) therapy.

- Factor VII deficiency is associated with moderate to severe bleeding.

- The combination of a prolonged prothrombin time and normal partial thromboplastin time may indicate factor VII deficiency.

People with severe factor VII deficiency:

- Are prone to joint bleeds

- In addition to spontaneous nosebleeds, people can experience bleeds in the stomach, intestines and urinary tract

- Head bleeds and muscle bleeds have also been reported

- Women can have severe menorrhagia

The factor VII assay is a blood test to measure the activity of factor VII. This is one of the proteins in the body that helps the blood clot.

The Factor VII protein is part of the cascade of clotting factors that form the chain leading to a protective blood clot. Factor VII deficiency is usually severe. In fact, patients with less than 1% Factor VII activity experience similar symptoms to hemophilia.

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Written by Healthmatters Editorial Team

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