Cytomegalovirus (CMV) is an opportunistic herpesvirus belonging to the Betaherpesvirinae subfamily, which is classified as herpes type-5. After primary infection, CMV can infect a variety of cell types such as epithelial cells of salivary glands, large intestine, lungs, smooth muscle, endothelial cells, liver, kidney, fibroblasts, neuronal cells and various myeloid cells. Persistent CMV has been implicated in systemic lupus erythematosus, multiple sclerosis, systemic sclerosis, type 1 diabetes and Sjögren’s syndrome.
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