Cryoglobulin, Qualitative with Reflex to Quantitative and Immunofixation – Labcorp Test 001594
Labcorp's Cryoglobulin, Qualitative with Reflex to Quantitative and Immunofixation is a diagnostic assay designed to detect and characterize cryoglobulins in serum. Cryoglobulins are abnormal proteins that precipitate from blood at temperatures below 37°C and dissolve upon rewarming. Their presence can lead to various clinical manifestations, including vasculitis, purpura, and neuropathy.
Clinical Utility
This test is particularly useful in evaluating patients with suspected cryoglobulinemia associated with:
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Hematologic disorders such as Waldenström macroglobulinemia, multiple myeloma, and chronic lymphocytic leukemia.
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Autoimmune diseases including systemic lupus erythematosus (SLE) and rheumatoid arthritis.
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Chronic infections, notably hepatitis C.
The test aids in identifying the underlying cause of symptoms like cold-induced skin lesions, joint pain, and peripheral neuropathy.
Interpretation
A negative result indicates no cryoglobulins detected. Positive results are reported as percentages and further analyzed to determine the cryoglobulin type. The presence of cryoglobulins, especially in the context of the aforementioned conditions, can guide clinicians in diagnosis and management strategies.
For more detailed information or to order the test, please visit Labcorp's official page.
Cryoglobulin, Ql, Serum, Rflx
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