Coproporphyrin III is a porphyrin derivative.
Small amounts of porphyrins (coproporphyrin) are excreted in normal human urine. Coproporphyrin also is present in bile and feces.
By convention, the term porphyria is used to define those disease states that have a hereditary basis and increased urinary or fecal excretion of uroporphyrins and coproporphyrins.
Porphyria can affect the nervous system or skin. Sometimes both are affected. The condition may or may not cause symptoms. Symptoms may develop over hours or days and last for days or weeks. Symptoms may be brought on by various medicines, smoking, drinking alcohol, weight loss, pregnancy, infections, or major surgery.
Symptoms include:
– Skin problems after sun exposure
– Pain, especially belly pain
– Numbness and tingling
– Digestive upset
– Personality changes
– Mental disorders
– Rapid heart rate and high blood pressure
– Painful urination
References:
– https://www.sciencedirect.com/topics/neuroscience/coproporphyrin
– https://emedicine.medscape.com/article/205374-workup
– https://www.medchemexpress.com/Coproporphyrin_III.html
– https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304676/
– https://www.ncbi.nlm.nih.gov/pubmed/8961873
– https://www.ncbi.nlm.nih.gov/pubmed/15661580
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