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Home › Research › Lyme Testing: Borrelia burgdorferi LFA-1
Lyme Testing

Borrelia burgdorferi LFA-1

By Healthmatters Editorial Team
Peer-reviewed sources
0-1 (negative)
0-1 is the stimulation index, which equals the negative control. 1 spot is, according to the manufacturer, not significant for an infection. Nevertheless, EliSpot results have to be interpreted within the patient’s overall clinical picture. A negative result does not completely exclude the exposure to the pathogen or infection being tested.
>3 (positive)
Borrelia burgdorferi LFA-1 (Lymphocyte Function Antigen 1): Own body protein + Borrelia burgdorferi sensu stricto (shared epitope). Often associated with autoimmune diseases: collagenosis, Rheumatoid Arthritis, vasculitis (ANA, CCP antibodies, ANCA) It helps to decide whether the patient is suffering from an active infection or an autoimmune disease.

Borrelia burgdorferi LFA-1 (Lymphocyte Function Antigen 1): Own body protein + Borrelia burgdorferi sensu stricto (shared epitope). Often associated with autoimmune diseases: collagenosis, Rheumatoid Arthritis, vasculitis (ANA, CCP antibodies, ANCA)

It helps to decide whether the patient is suffering from an active infection or an autoimmune disease.

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Written by Healthmatters Editorial Team
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