Anti CV2 antibodies are a group of antibodies that react with a 66 kd brain protein belonging to the family of CRMP proteins. The manifestations associated with anti CV2 antibodies include cerebellar degeneration, uveitis, and peripheral neuropathy, and mixed axonal and demyelinating peripheral neuropathy.
References:
Antoine JC, Honnorat J, Camdessanché JP, Magistris M, Absi L, Mosnier JF, Petiot P, Kopp N, Michel D. Paraneoplastic anti-CV2 antibodies react with peripheral nerve and are associated with a mixed axonal and demyelinating peripheral neuropathy. Ann Neurol. 2001 Feb;49(2):214-21. doi: 10.1002/1531-8249(20010201)49:2<214::aid-ana41>3.0.co;2-w. PMID: 11220741.
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