The Lymphocyte MAP
Performed by: Cyrex Laboratories
Comprehensive Lymphocyte Immunophenotyping: A Breakthrough in Immune System Analysis
FEATURES
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Unique Immunotypes for Comprehensive Insights
- The panel includes 14 immunotypes designed to uncover critical immune system trends by analyzing a wide range of determinants.
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Advanced Th1/Th2 Balance Analysis (Immunotypes 6 & 7)
- Utilizes the proprietary Cyrex Fluorescence-Activated Cell Test (Cyrex FACT™) to assess T-helper-1 (Th1) and T-helper-2 (Th2) dominance. Unlike traditional methods that measure cytokine levels, Cyrex FACT™ analyzes specific CD markers on the surface of Th1 and Th2 cells, offering a more precise and actionable insight into immune balance.
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Regulatory T Cells (Tregs, Immunotype 8)
- Evaluates Tregs, essential for maintaining the balance between Th1 and Th2 responses. Low Treg levels can contribute to issues such as immune suppression, autoimmune disorders, increased infections, and cancer.
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Th17 Dominance (Immunotype 9)
- Includes a specialized Cyrex FACT™ process to identify Th17 dominance via CD markers, avoiding reliance on IL-17 blood levels for a more accurate depiction of immune dynamics.
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Natural Killer (NK) Cell Patterns (Immunotypes 12 & 13)
- Identifies imbalances in NK cells, cytotoxic NK cells, and NK T cells, which are vital for targeting pathogens and cancer cells.
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CD57+ NK Cells and Their Role (Immunotype 14)
- Evaluates CD57+ NK cells, long-lived immune cells critical for targeting infected and cancerous cells, particularly in aging populations. High levels of CD57+ NK cells are linked to better outcomes in cancer and autoimmune diseases, while low levels may indicate reduced survival rates.
CLINICAL USES
- Immune System Assessment: Evaluates the immune system's cellular integrity to detect weaknesses or imbalances.
- Pre-Disease Detection: Identifies abnormalities before disease onset, enabling early intervention.
- Personalized Treatment Design: Guides the creation of customized treatment protocols during active disease stages.
- Treatment Monitoring: Tracks patient recovery and medication effectiveness post-treatment.
Why Choose the Lymphocyte MAP™ by Cyrex Laboratories?
The Lymphocyte MAP™ is an advanced, comprehensive diagnostic panel designed to assess the immune system's functionality and integrity at the cellular level. By analyzing 29 key lymphocyte biomarkers, including Th1, Th2, Treg, Th17, and various NK cell types, this test provides a detailed overview of immune health.
Key features include:
- The use of Cyrex FACT™, a cutting-edge process for precise immune profiling.
- The ability to detect immune deficiencies, inflammation, autoimmunity, allergies, asthma, and cancer at the cellular level.
This test is ideal for:
- Proactive health optimization for individuals seeking to enhance longevity and resilience.
- Patients with autoimmune diseases, chronic infections, or inflammation, such as those with post-viral syndromes or COVID-19 exposure.
By providing healthcare practitioners with actionable insights, the Lymphocyte MAP™ supports tailored treatment strategies to restore immune balance and improve patient outcomes.
Maximize your immune health with the Lymphocyte MAP™ by Cyrex Laboratories—the gold standard in immune system evaluation.
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Biomarkers included in this panel:
% B Cell
B cells, also known as B lymphocytes, are a crucial component of the adaptive immune system. They function primarily by producing antibodies against antigens, which are substances recognized as foreign by the immune system. These antibodies are speci
Learn more% CD3- CD57+ Lymphocyte
% CD57+ CD16+ NK
This result reports the percentage of lymphocytes identified as CD57+ CD16+ natural killer (NK) cells. CD57 marks a more mature NK-cell population, while CD16 helps these cells recognize antibody-coated targets. Read it with Total CD57+ CD16+ NK Cell
Learn more% CD57+ CD8+ T Cell
The marker % CD57+ CD8+ T cells provides insightful data into an individual's immune status, specifically reflecting the subset of natural killer T cells (NKT-like cells) that exhibit both CD57 and CD8 markers. CD57, a marker for terminal diff
Learn moreThe % Cytotoxic (CD8) T Cell marker reflects the proportion of CD8+ T cells among total lymphocytes or T-helper cells. CD8+ T cells, also known as cytotoxic T lymphocytes (CTLs), are a critical component of the adaptive immune system. Their primary r
Learn more% Cytotoxic NK cells (CD16+)
The percentage of Cytotoxic NK (Natural Killer) cells expressing CD16+. CD16+, also known as FcγRIII, is a low affinity receptor for the Fc region of immunoglobulins G (IgG), found on the surface of NK cells, and plays a pivotal role in antibod
Learn moreThe % Lymphocyte measures the proportion of white blood cells that are lymphocytes, a critical component of the adaptive immune system including T cells, B cells, and natural killer cells. It reflects how the body’s immune defenses are distribu
Learn more% NK Cell (CD56+)
The marker "% NK Cell (CD56+)" signifies the percentage of natural killer (NK) cells that express the CD56 antigen, a pivotal component in the assessment of immune health and functionality. NK cells, a critical subset of lymphocytes in the
Learn moreThe % NKT (CD56+ CD16+ T Cell) marker measures the proportion of natural killer T (NKT) cells within the total lymphocyte population. NKT cells are a unique subset of immune cells that share characteristics of both T lymphocytes and natural killer (N
Learn more% Regulatory T Cell
The % Regulatory T Cell (Treg) marker on the Lymphocyte MAP™ panel represents the proportion of Tregs within the total lymphocyte population. Regulatory T cells (Tregs) are a specialized subset of CD4+ T-helper cells critical for maintaining im
Learn more% T Cell
The "% T Cell" marker refers to the percentage of T cells in the lymphocyte population of the blood. T cells, a type of white blood cell, are central to the adaptive immune response, playing a pivotal role in immune regulation and response
Learn more% T-Helper (CD4) Cell
This result shows the percentage of lymphocytes that are CD4 helper T cells, which coordinate immune responses. The percentage describes their share of lymphocytes; Total T-Helper (CD4) Cell describes their number per microliter. The two can fall in
Learn more% T-Helper-1 Cell
This result reports the percentage of lymphocytes classified as T-helper-1 (Th1) cells by the Cyrex method. Th1 cells support cellular immune responses. Cyrex uses surface markers rather than measuring circulating Th1-associated cytokines. Read the p
Learn more% T-Helper-17
The % T-Helper-17 (Th17) marker plays an important role in the evaluation of the immune system's state, particularly in the context of inflammation and autoimmunity. Th17 cells, a subset of T-helper cells, are primarily known for their involvemen
Learn more% T-Helper-2 Cell
The % T-Helper-2 Cell marker is a critical component in evaluating immune system functionality, particularly in the context of immune system balance and potential disorders. T-Helper-2 cells, often denoted as Th2 cells, are a subtype of T cells that
Learn moreThe CD4/CD8 ratio is a critical marker of immune system health. It measures the balance between CD4+ T-helper cells and CD8+ cytotoxic T cells, two major subtypes of T lymphocytes. These cells play complementary roles in immune defense: CD4+ T-
Learn moreT Cell/B Cell Ratio
The T Cell/B Cell Ratio is a sophisticated biomarker indicative of the adaptive immune system's balance and functionality. This ratio compares the quantity of T cells, which are primarily responsible for cell-mediated immunity, to B cells, which
Learn moreThe TH1/TH2 ratio measures the balance between T-helper type 1 (TH1) and T-helper type 2 (TH2) cells. These are subsets of CD4+ T-helper cells that regulate the immune system by driving different types of immune responses: TH1 Cells: Promote ce
Learn moreTh17/Treg Ratio
The Th17/Treg ratio is a critical marker offering significant insights into the immune system's regulatory mechanisms. Th17 cells (T-helper 17) and Treg cells (regulatory T cells) represent two distinct subsets of CD4+ T cells with opposing funct
Learn moreTotal B Cell
The Total B Cell marker is a critical indicator used to assess the status of B cells within the immune system. B cells, also known as B lymphocytes, play a pivotal role in the adaptive immune response, primarily responsible for the production of a
Learn moreTotal CD3- CD57+ Lymphocyte
The Total CD3- CD57+ Lymphocyte marker is offering insights into the immune system's state, particularly in the context of chronic infections and certain health conditions. This marker focuses on a subset of lymphocytes that are characterized by
Learn moreTotal CD57+ CD16+ NK Cell
This result counts CD57+ CD16+ natural killer (NK) cells per microliter of blood. It measures the size of a mature NK-cell subset rather than its share of all lymphocytes. Read it with % CD57+ CD16+ NK and the other NK-cell counts. A cell count does
Learn moreTotal CD57+ CD8+ T Cell
The Total CD57+ CD8+ T Cell marker plays a crucial role in immunological assessments. This marker is particularly significant because CD57+ CD8+ T cells are a subset of natural killer T cells (NKT cells) and cytotoxic T cells, which are integral comp
Learn moreThis result counts CD8 T cells per microliter of blood. These cells help eliminate infected or abnormal cells. The count shows how many are circulating, not how effectively they respond to a threat. Read it with % Cytotoxic (CD8) T Cell, Total T-Help
Learn moreTotal Cytotoxic NK cells (CD16+)
Total Cytotoxic NK (Natural Killer) cells, identified by the CD16+ marker, represent a crucial component in the innate immune system, playing a significant role in the body's first line of defense against tumors and virally infected cells. NK
Learn moreThis result counts circulating lymphocytes per microliter of blood, including T cells, B cells, and natural killer cells. A total within range can still contain an individual subset outside range. Read it with the individual cell counts to understand
Learn moreTotal NK Cell (CD56+)
Total NK cells (CD56+) represent a critical subset of lymphocytes pivotal for innate immunity, providing the first line of defense against tumors and a variety of pathogens. Natural Killer (NK) cells are characterized by their expression of the CD56
Learn moreTotal NKT (CD56+ CD16+ T Cell)
The Total NKT (CD56+ CD16+ T Cell) marker measures the absolute count of natural killer T (NKT) cells in the blood. NKT cells are a specialized group of immune cells that share characteristics of both T lymphocytes (adaptive immunity) and natural kil
Learn moreTotal Regulatory T Cell (Treg)
Total Regulatory T cells (Treg) serve as a crucial marker for understanding immune regulation and potential autoimmune dysregulation within the body. Tregs, a subset of T cells characterized by the expression of CD4, CD25, and the transcription facto
Learn moreThis result counts circulating T lymphocytes per microliter of blood. T cells include helper and cytotoxic populations with different roles in immune defense. Read the total with Total T-Helper (CD4) Cell, Total Cytotoxic (CD8) T Cell, and % T Cell.
Learn moreThis result counts CD4 helper T cells per microliter of blood. These cells coordinate immune responses. The count and % T-Helper (CD4) Cell can fall in different range categories, so read them together with the CD8 results and CD4/CD8 Ratio. They des
Learn moreTotal T-Helper-1 Cell
The Total T-Helper-1 Cell marker serves as a critical component in the evaluation of immune system functionality, particularly in the adaptive immune response. T-Helper-1 (Th1) cells are a subset of CD4+ T cells, which are pivotal in orchestrating th
Learn moreTotal T-Helper-17 (Th17)
The Total T-Helper-17 (Th17) marker is a critical component in evaluating immune system functionality, particularly in the context of immune response regulation. T-Helper 17 (Th17) cells, a subset of pro-inflammatory T-helper cells, play a pivotal ro
Learn moreTotal T-Helper-2 Cell
Total T-Helper-2 (Th2) cells are a subset of the CD4+ T cells, playing a pivotal role in the adaptive immune response. They are characterized by their function in helping B cells to produce antibodies and are crucial in the defense against extracellu
Learn moreTotal WBC
The Total WBC (White Blood Cell) count measures the total number of white blood cells present in the blood, which are essential components of the immune system. White blood cells are responsible for defending the body against both infectious disease
Learn more